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Reprogramming the Cerebral Cortex

Reprogramming the Cerebral Cortex

Plasticity following central and peripheral lesions

9780198528999
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Description
The brain has a remarkable ability to adapt in the event of damage - in many cases shifting responsibility for specific cognitive functions to other non-damaged brain regions. This plasticity can be crucial in aiding recovery from stroke, trauma, and peripheral damage such as eye or ear damage. Over the past thirty years our view of cortical plasticity has evolved greatly. Early studies suggested that changes to cortical function due to peripheral lesions could only occur duringdevelopment and that these plastic changes were specific to a particular temporal window or critical period. Over time, it has been demonstrated that cortical modifications as a consequence of either peripheral or central lesions can induce adaptive, or beneficial, changes in cortical function in aneffort to preserve or enhance function. More recently, studies have identified that many of these adaptive changes, once thought only possible in the developing brain, are also possible in the mature or developed brain. At present, many laboratories are defining the beneficial capabilities of cerebral cortex plasticity, upon which many proactive and therapeutic strategies may be developed in order to maximiSe the reprogramming capabilities of the cerebrum. Reprogramming the Cerebral Cortex describes these exciting studies and examines adaptive cortical plasticity in a variety of systems (visual, auditory, somatomotor, cross-modal, language and cognition). The book leads the reader through the complexities and promise of neuroplasticity, and presents insights into current and future research and clinical practice. It is unique in looking at the beneficial capabilities of cerebral cortex plasticity, upon which many proactive and therapeuticstrategies may be developed. The book will be a valuable resource for behavioural, systems, computational and cognitive neuroscientists, as well as clinicians and neuropsychologists.
Product Details
OUP Oxford
85469
9780198528999
9780198528999

Data sheet

Publication date
2006
Issue number
1
Cover
hard cover
Pages count
452
Dimensions (mm)
175 x 253
Weight (g)
952
  • Vision; Reprogramming of striate and extrastriate visual cortices following retinal lesion; Visual cortex reprogramming following retinal lesions or artificial scotomas: perceptual effects and neural circuitry; Remodelling of cortical connections and enhanced long-term potentiation after lesions of the visual cortex; Reorganization of cerebral functions following primary visual cortex damage during infancy; Behavioral and neural alterations following V1 damage in immature primates; Neurological changes underlying motion percpetion plasticity after lesions of extrastriate visual cortex in adult cats; Audition; A time-line of auditory cortical reorganization after noise-induced hearing loss; Development, maintenance and plasticity of tonotopic projections from cochlea to auditory cortex; Central auditory plasticity in mouse models of progressive sensorineural hearing loss; Recruitment of the auditory cortex in congenitally deaf cats; Critical periods for human cortical development: an ERP study in children with cochlear implant; Somatomotor; Neuronal plasticity after stroke: evidence from animal models of postinjury recovery; Reprogramming surviving motor cortex after stroke; Cerebral reprogramming underlying functional recovery following stroke; Reorganization of somatosensory and motor cortex followinig peripheral nerve or spinal cord injury in primates; Critical periods for functional recovery after cortical injury during development; Reprogramming the motor cortex for functional recovery after neonatal or adult unilateral lesion of the corticospinal system in the macaque monkey; Adaptive functional changes in the cerebral cortex during multiple sclerosis; Cortical reprogramming: significance for phantom phenomena and clinical implications; Cross-modal; Reprogramming cortex: the consequences of cross-modal plasticity during development; Adaptive plasticity and sensory substitution in the cerebral cortex; Activation of the visual cortex by Braille reading in blind subjects; Sound localization in early-blind human subjects: evidence for adaptive cortical plasticity; Cognition; The longitudinal study of spatial cognitive development inchildren with pre- or perinatal focal brain injury: evidence for cognitive compensation and for the emergence of alternative profiles of brain organization;
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