Dendrites are complex neuronal structures that receive and integrate synaptic input from other nerve cells. They therefore play a critical role in brain function. Although dendrites were discovered over a century ago, due to the development of powerful new techniques there has been a dramatic resurgence of interest in the properties and function of these beautiful structures. This is the third edition of the first book devoted exclusively to dendrites. It contains a comprehensive survey of the current state of dendritic research across a wide range of topics, from dendritic morphology, evolution, development, and plasticity through to the electrical, biochemical and computational properties of dendrites, and finally to the key role of dendrites in brain disease. The third edition has been thoroughly revised, with the addition of a number of new chapters andcomprehensive updates or rewrites of existing chapters by leading experts.Dendrites will be of interest to researchers and students in neuroscience and related fields, as well as to anyone interested in how the brain works.
Dendrite structure; Evolution and Scaling of Dendrites; Dendrite Development; Molecular Determinants of Dendrite and Spine Development; Local translation in dendrites; Structure and Molecular Organization of the Postsynaptic Density; Subcellular Distribution of Ligand- and Voltage-Gated Ion Channels; Neurotransmitter-gated ion channels in dendrites; Dendritic Voltage-gated Ion Channels; Biochemical compartmentalization in dendrites; Spine Calcium Signaling; Principles of Dendritic Integration; Dendritic integration in vivo; Modeling dendrites: A personal perspective; A theoretical view of the neuron as an input-output computing device; Towards a simplified model of an active dendritic tree; Modelling dendrite shape; Functional Plasticity at Dendritic Synapses; Structural plasticity in dendrites and spines; Molecular signaling during plasticity of dendritic spines; Dendrites as Transmitters; Dendritic connectomics; Linking Dendritic Processing to Computation and Behavior in Invertebrates; Dendrites and Disease; The Future of Dendrite Research;
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