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Motor Neuron Diseases: Causes, Classification & Treatments
9781631173424
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Description
Motor neuron disease (MND), also commonly known as amyotrophic lateral sclerosis (ALS), is a chronic neurodegenerative disorder of the motor system in adults, characterised by the loss of motor neurons in the cortex, brain stem and spinal cord. This book presents current research from across the globe in the study of the causes, classification and treatments of MND, including membrane trafficking defects as determinants of motor neuron susceptibility and degeneration in ALS; motorneuron specific calcium dysregulation and perturbed cellular calcium homeostasis in ALS; stem cells and their application in ALS treatment; excitotoxicity and selective motor neuron degeneration and therapeutic intervention and assistive technology treatments.
Product Details
74518
9781631173424
9781631173424
Data sheet
- Publication date
- 2014
- Issue number
- 1
- Cover
- paperback
- Pages count
- 244
- Dimensions (mm)
- 180.00 x 260.00
- Weight (g)
- 458
- Preface; Motor Neuron Disease:: Causes, Classification & Treatments; Membrane Trafficking Defects as Determinants of Motor Neuron Susceptibility & Degeneration in ALS; Motoneuron Specific Calcium Dysregulation & Perturbed Cellular Calcium Homestasis in Amyotrophic Lateral Sclerosis:: Recent Advances Gained from Genetically Modified Animals & Cell Culture Models; Treatment of ALS Utilizing a Stem Cell Strategy; TDP-43-Immunoreactive Pathology in Frontotemporal Lobar Degeneration with TDP Proteinopathy (FTLD-TDP) with & without Associated Motor Neuron Disease (MND); Excitotoxicity & Selective Motor Neuron Degeneration; Stem Cell Application in Amyotrophic Lateral Sclerosis:: Growth Factor Delivery & Cell Therapy; Therapeutic Intervention in Spinal & Bulbar Muscular Atrophy (SBMA).
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