This book presents current research in the study of neurologic disorders. Topics discussed include oxidative stress-mediated neurodegeneration; mechanisms of the motoneuron stress response and its relevance in neurodegeneration; genetics and molecular biology of Alzheimers disease and frontotemporal lobar degeneration; molecular imaging and Parkinsons disease; mitochondrion selective antioxidants as drug treatments for Alzheimers disease; the role of vitamins in vascular dementia and biofluid protein biomarkers for the diagnosis of vascular dementia.
Preface; Oxidative Stress-Mediated Neurodegeneration:: A Tale of Two Models; Mechanisms of the Motoneuron Stress Response & its Relevance in Neurodegeneration; Methylene Blue Induces Mitochondrial Complex IV & Improves Cognitive Function & Grip Strength in Old Mice; Receptor Specific Features of Excitotoxicity Induced Neurodegeneration; Mitochondrial Uncoupling Proteins:: Therapeutic Targets in Neurodegeneration?; Targeting Caspases in Neonatal Hypoxic-Ischemic Brain Injury & Traumatic Brain Injury; Alterations in N-methyl-D-Aspartate (NMDA) Receptor Function & Potential Involvement in Anesthetic-Induced Neurodegeneration; Genetics & Molecular Biology of Alzheimers Disease & Frontotemporal Lobar Degeneration:: Analogies & Differences; The Cholinergic Neuron in Alzheimers Disease; Retinal Neurodegeneration is an Early Event in the Pathogenesis of Diabetic Retinopathy:: Therapeutic Implications.
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