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Parkinson's Disease and Related Disorders Part I
Handbook of Clinical Neurology (Series Editors: Aminoff, Boller and Swaab)
9780444519009
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Description
The two volumes on Parkinsons disease in the Handbook of Clinical Neurology (Series Editors:: Michael J. Aminoff, Department of Neurology, University of California, San Francisco, USA; François Boller, Bethesda, USA; Dick F. Swaab, Netherlands Institute for Neuroscience, Amsterdam, the Netherlands) cover a group of disorders that constitute the commonest of neurodegenerative diseases and one that is assuming ever greater importance with the ageing of the population in developed countries. The coverage reflects the dramatic advances in understanding of the biochemical background of parkinsonism and the resulting developments in the pharmacological management of the disease. These volumes give a comprehensive account of the subject for both clinical neurologists and those researching in the neurosciences.
Part I covers the scientific background, general aspects of Parkinsons disease, clinical aspects and etiology. Part II covers the medical and surgical treatment of Parkinsons disease, complications of therapy and the other parkinsonian syndromes.
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Part I covers the scientific background, general aspects of Parkinsons disease, clinical aspects and etiology. Part II covers the medical and surgical treatment of Parkinsons disease, complications of therapy and the other parkinsonian syndromes.
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Product Details
35010
9780444519009
9780444519009
Data sheet
- Publication date
- 2007
- Issue number
- 1
- Cover
- hard cover
- Pages count
- 656
- Dimensions (mm)
- 246 x 189
- Weight (g)
- 2009
- Section 1: Scientific foundation
Anatomy and physiology of the basal ganglia: relevance to parkinsons disease and related disorders. Functional neurochemistry of the basal ganglia. Dopamine receptor pharmacology.
Section 2: General aspects of Parkinsons disease
History of Parkinsons disease. Epidemiology of Parkinsons disease. Neurochemistry of the basal ganglia in Parkinsons disease. The neuropathology of parkinsonism. Imaging Parkinsons disease. Parkinsons disease: animal models.
Section 3: Clinical aspects
Scales to measure parkinsonism. Motor symptoms in Parkinsons disease. Autonomic dysfunction in Parkinsons disease. Sleep in Parkinson syndromes. Sensory symptoms in Parkinsons disease. Speech disorders in Parkinsons disease and the effects of pharmacological, surgical and speech treatment with emphasis on Lee Silverman voice treatment. Clinical features, pathophysiology and treatment of dementia associated with Parkinsons disease. Disorders of mood and affect in Parkinsons disease. Neurobehavioral disorders in Parkinsons disease. Early detection of Parkinsons disease.
Section 4: Etiology
Mitochondria in the etiology of Parkinsons disease. Iron as a trigger of neurodegeneration in Parkinsons disease. Oxidative stress and Parkinsons disease. Neurotrophic factors and Parkinsons disease. Neuroinflammation and Parkinsons disease. Excitotoxicity. Protein handling dysfunction in Parkinsons disease. Programmed cell death in Parkinsons disease.
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