Outbreak:: Cases in Real-World Microbiology, 2nd Edition, is the newest edition of this fascinating textbook designed for introductory microbiology students and instructors. Thoroughly revised, this collection of case studies of real-world disease outbreaks, generously illustrated in full color, offers material that directly impacts college-level students, while the books unique presentation offers instructors the flexibility to use it effectively in a number of ways. More than 90 outbreak case studies, organized into six sections according to the human body system affected, illustrate the wide range of diseases caused by microbial pathogens. The studies are presented at differing levels of difficulty and can be taught at all undergraduate levels. Each case study includes questions for students to think about, discuss, and answer, and the book includes an appendix that directs students to the specific reference material on which each case was based, providing the opportunity to investigate further and to apply the reference content to the case being studied. Each of the six sections of the book concludes with a College Perspective and a Global Perspective case study. The College Perspective provides a direct and practical link between the microbiology course and the daily lives of students. The Global Perspective connects students with outbreaks that have occurred in countries around the world to facilitate understanding of the social, religious, economic, and political values at play in the treatment and prevention of infectious disease. At the end of every section, detailed descriptions offer concise yet complete information on each disease involved in that section.
Introduction xiii About the Author xvii Section I Outbreaks of Diseases of the Respiratory Tract 1 Outbreak I-1 A Legionellosis Outbreak—Barceloneta 4 Outbreak I-2 An Outbreak of Respiratory Syncytial Virus Infection—Arviat, Canada 5 Outbreak I-3 A Tuberculosis Outbreak in a Prison Housing Inmates Infected with HIV—South Carolina 7 Outbreak I-4 An Otitis Media Outbreak in a Child Care Center—Georgia 9 Outbreak I-5 An Outbreak of a Rash—Venezuela and Colombia 11 Outbreak I-6 Hantavirus Pulmonary Syndrome Outbreak—Vermont 13 Outbreak I-7 A Diphtheria Outbreak—Newly Independent States of the Former Soviet Union 15 Outbreak I-8 An Outbreak of Mycoplasmal Pneumonia—Ohio 17 Outbreak I-9 A Pneumonia Outbreak in a Nursing Home—New Jersey 18 Outbreak I-10 Past and Future Pandemics of Influenza A—Worldwide, 1918 to Present 19 Outbreak I-11 A Pharyngitis Outbreak in the Marine Corps—San Diego 21 Outbreak I-12 A Measles Outbreak in Kosovar Refugee Children—Albania 23 Outbreak I-13 A Swimming Pool-Related Outbreak of Pharyngitis and Conjunctivitis—Spain 25 Outbreak I-14 A Cruise Ship-Associated Legionnaires’ Disease Outbreak 27 Outbreak I-15 A Pertussis Epidemic—Washington State 29 College Perspective Outbreak I-16 A Mumps Outbreak on a University Campus—California 31 Global Perspective Outbreak I-17 A Diphtheria Outbreak—Colombia 34 Reference Material 37 Section II Outbreaks of Disease of the Gastrointestinal Tract 51 Outbreak II-1 A Salmonella enterica serovar Enteritidis Outbreak from Eating Eggs—Multistate 54 Outbreak II-2 A Diarrhea Outbreak Associated with Swimming Pool Use—Ohio 56 Outbreak II-3 Diarrhea among Attendees of the Washington County Fair—New York 58 Outbreak II-4 An Amoebiasis Outbreak—Georgia 60 Outbreak II-5 A Typhoid Fever Outbreak Linked with a Frozen Fruit Drink—Florida 62 Outbreak II-6 A Diarrhea Outbreak in a Day Care Nursery—Juneau, Alaska 64 Outbreak II-7 A Foodborne Outbreak of Bloody Diarrhea—Multistate 66 Outbreak II-8 A Multistate Outbreak of Listeriosis—Northeastern United States 68 Outbreak II-9 An Outbreak of Rotaviral Gastroenteritis among Children—Jamaica 69 Outbreak II-10 Bloody Diarrhea Associated with Eating Ground Beef—United States 71 Outbreak II-11 A Hepatitis Outbreak Associated with Restaurant Onions—Pennsylvania 73 Outbreak II-12 A Rotavirus Outbreak among College Students—District of Columbia 75 Outbreak II-13 A Cholera Outbreak in a Refugee Camp—Democratic Republic of the Congo 77 Outbreak II-14 A Diarrhea Outbreak Associated with Raw Milk and Cheese Consumption—Pennsylvania 80 Outbreak II-15 A Listeriosis Outbreak Associated with Pasteurized Milk—Massachusetts 83 Outbreak II-16 An Outbreak Associated with Seasonal Consumption of Raw Ground Beef—Wisconsin 85 College Perspective Outbreak II-17 A Diarrhea Outbreak Associated with an Adventure Race—Nevada 87 Global Perspective Outbreak II-18 A Case-Control Study of an Outbreak of Clostridioides difficile at a Tertiary Care Medical Center—Amsterdam, The Netherlands 89 Reference Material 93 Section III Pathogens and Diseases That Are Transmitted Sexually 105 Outbreak III-1 An STD Outbreak among Teenagers—Georgia 107 Outbreak III-2 An STD Outbreak among Hispanic Men—California 109 Outbreak III-3 An Outbreak of HIV Disease in the Adult-Film Industry—California 111 Outbreak III-4 An Outbreak of Azithromycin-Resistant Gonorrhea—Kansas City 113 Outbreak III-5 Invasive Cervical Cancer among Women—United States 115 Outbreak III-6 A Proctitis Outbreak among Men Who Have Sex with Men—Netherlands 117 Outbreak III-7 A Syphilis Outbreak Connected to a Cybersex Chat Room—San Francisco 119 Outbreak III-8 STDs in Operation Iraqi Freedom/Operation Enduring Freedom—Iraq 121 Outbreak III-9 Herpes Simplex Virus Type 2 Infection among U.S. Military Service Members 123 College Perspective Outbreak III-10 STD Risk Increased by Using the Internet To Find Casual Sexual Partners 125 Global Perspective Outbreak III-11 Impact of AIDS Worsens Famine—Southern Africa 127 Reference Material 129 Section IV Outbreaks of Diseases of the Skin, Soft Tissues, and Eyes 139 Outbreak IV-1 An Outbreak of Pseudomonas Dermatitis from Hotel Pool and Hot Tubs—Colorado 141 Outbreak IV-2 An Outbreak of Skin Lesions in a Wrestling Team—Alaska 143 Outbreak IV-3 An Outbreak of Conjunctivitis at an Elementary School—Maine 144 Outbreak IV-4 A Measles Outbreak among Internationally Adopted Children—United States 146 Outbreak IV-5 An Outbreak of “Flesh-Eating Bacterium” Disease—Saint John, Brunswick, Canada 148 Outbreak IV-6 An Outbreak of Invasive Group A Streptococcus at a Child Care Center—Boston 150 Outbreak IV-7 An Outbreak of a Rash at a Camp for HIV-Infected Children—Connecticut 152 Outbreak IV-8 A Rubella Outbreak—Arkansas 153 Outbreak IV-9 An Outbreak of Invasive Disease Associated with Varicella in a Child Care Center—Boston 155 Outbreak IV-10 An Outbreak of Boils Associated with Footbaths at a Nail Salon—California 157 Outbreak IV-11 An Outbreak of Boils Associated with Steam Bathing, Alaska 159 Outbreak IV-12 A Skin Infection Outbreak at a Local School—Houston, Texas 161 Outbreak IV-13 An Outbreak of MRSA at Surgical Sites—Paris 163 Outbreak IV-14 An Outbreak of Necrotizing Fasciitis and Cellulitis Associated with Vein Sclerotherapy—Australia 165 College Perspective Outbreak IV-15 Skin Infections among Tattoo Recipients—Ohio 167 Global Perspective Outbreak IV-16 A Gas Gangrene Outbreak after a Tsunami—Papua New Guinea 170 Reference Material 171 Section V Outbreaks of Diseases of the Cardiovascular and Lymphatic Systems 181 Outbreak V-1 An Outbreak of Typhus—Burundi 183 Outbreak V-2 An Outbreak of Cyclic Fevers—India 185 Outbreak V-3 An Outbreak of Mononucleosis—Puerto Rico 186 Outbreak V-4 Fever in a Traveler Returning from Venezuela—California 187 Outbreak V-5 Cases of Rash and Fever, One Fatal, in a Family Cluster—Kentucky 189 Outbreak V-6 An Outbreak of Ebola Hemorrhagic Fever—Uganda 191 Outbreak V-7 An Outbreak of Leptospirosis during Eco-Challenge—Malaysia 193 Outbreak V-8 A Dengue Fever Outbreak—Puerto Rico 194 Outbreak V-9 A Disease Outbreak Associated with International Travel—Chicago 196 Outbreak V-10 Pseudomonas Bloodstream Infections Associated with a Heparin-Saline Flush—Missouri 199 Outbreak V-11 A Brucellosis Outbreak Due to Unpasteurized Raw Goat Cheese—Andalusia, Spain 201 Outbreak V-12 An Acute Respiratory Illness Associated with Dried Animal Hides—New York City 203 Outbreak V-13 A Plague Outbreak—India 205 Outbreak V-14 A Hepatitis Outbreak from a Pain Clinic—Oklahoma 207 Outbreak V-15 An Outbreak of Staphylococcus aureus with Increased Vancomycin Resistance—Illinois 209 College Perspective Outbreak V-16 An Outbreak of Lyme Disease—United States 211 Global Perspective Outbreak V-17 The Zika Virus Spreads from Uganda to the United States 213 Reference Material 217 Section VI Outbreaks of Diseases of the Nervous System 231 Outbreak VI-1 An Outbreak of Acute Flaccid Paralysis—Cape Verde 232 Outbreak VI-2 An Outbreak of Paralysis from Eating Fermented Beaver Tails—Alaska 233 Outbreak VI-3 Rabies Infections from Organ Donor Tissues—Multistate 235 Outbreak VI-4 A Tetanus Outbreak—Puerto Rico 237 Outbreak VI-5 An Outbreak of Aseptic Meningitis among Recreational Vehicle Campers—Connecticut 239 Outbreak VI-6 A Mad Cow Disease Outbreak in Humans and Cattle—United States, Canada, Europe, and Japan 241 Outbreak VI-7 Foodborne Paralysis from Eating Home-Pickled Eggs—Illinois 243 Outbreak VI-8 An Outbreak of Encephalitis—New York 245 Outbreak VI-9 An Outbreak of Haemophilus influenzae Type b Meningitis—Alaska 247 Outbreak VI-10 An Outbreak of Foodborne Botulism from Home-Prepared Fermented Tofu—California 249 Outbreak VI-11 Meningitis among Travelers Returning from Saudi Arabia—United States 251 College Perspective Outbreak VI-12 Meningitis Outbreaks Traced to Raves and Clubs—Michigan and Argentina 253 Global Perspective Outbreak VI-13 An Outbreak of Pneumococcal Meningitis—Central African Republic 255 Reference Material 257 Appendix Selected Sources 265 Index 27
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