Clinical laboratory data are among the most detailed, objective, reliable and useful measures of patient characteristics contained in the medical record. The Editors intent in assembling this volume is to provide an introduction to standard techniques for managing and mining clinical data, and to illustrate these techniques with several applications related to laboratory medicine and associated research. The volume is divided into a foundations section, which provides a discussion of data mining techniques and tools, data warehousing and time series analysis, and an applications section that presents a set of projects comprising data.