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Successful Randomized Trials

Successful Randomized Trials

A Handbook for the 21st Century

9780781779456
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Description

This handbook is a ready reference on the theory and operation of modern large, multicenter randomized clinical trials, which have come to be the basis of evidence-based medicine. Written in a concise, engaging style geared to physicians, the book explains the rationale and theoretical foundations for clinical trials, the components of modern clinical trials including their functions and interactions, and practical considerations in the design and implementation of these studies including an introduction to the economics and business aspects.

Product Details
42021
9780781779456
9780781779456

Data sheet

Publication date
2008
Issue number
1
Cover
paperback
Pages count
224
Dimensions (mm)
133 x 213
Weight (g)
227
  • SECTION I CLINICAL TRIAL PRINCIPLES

    • CH. 1 Randomized Clinical Trials
    • CH. 2 Designing Clinical Trials
    • CH. 3 Randomization:: What It Is and How to Do It
    • CH. 4 Setting Sample Size for Randomized Clinical Trials
    • CH. 5 Analytic Approach and Methods
    • CH. 6 Ethical Considerations

    SECTION II Large Multicenter Trials:: Structure and Conduct

  • CH. 7 Study Organization and Governance
  • CH. 8 Quality Control and Quality Assurance
  • CH. 9 Quality Assurance:: Prevention of Missing Data

SECTION III THE FUTURE

CH. 10 Surrogate Endpoints CH. 11 Registries CH. 12 Gazing Into the Crystal Ball:: The Future of Randomized Clinical Trials

INDEX

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