In this issue of Critical Care Nursing Clinics, guest editor Shu-Fen Wung brings her considerable expertise to the topic of Updates on Human Factors and Technology in the ICU. Real-world human interaction and technology and devices are at the heart of care for patients in the intensive care unit. Nurses must address proper instruction, user-technology hazards, and improved nurse-technology interfaces in order to ensure optimal patient care and safety. This issue addresses these matters with articles ranging from intravenous smart pumps, to digital technology to promote family engagement, to technology to reduce pressure injuries, and many more.