In this issue of Infectious Disease Clinics of North America, guest editor Dr. Vincent B. Young brings his considerable expertise to the topic of Clostridioides difficile Infection. In the last decade there have been major changes in the diagnosis, epidemiology, and treatment of this important nosocomial infection. New treatments including new antibiotics and monoclonal antibodies have been developed to treat both initial episodes and recurrent CDI, and diagnostic and treatment guidelines have been created to reflect these developments. This issue addresses these changes to the clinical prevention, diagnosis, and treatment of CDI and also touches on advances in basic science that are more directly relevant to clinicians who encounter CDI in their daily professional practice.
Changes in the Epidemiology of Clostridioides difficile Infection Genomic Epidemiology of Clostridioides difficile The Transmission of Clostridioides (Clostridium) difficile with a One Health Perspective Diagnostic Approaches for Clostridioides difficile Infection Advances in the Medical Treatment of Clostridioides difficile Infection Management of Severe Clostridioides difficile Infection Microbiome Therapeutics for Clostridioides difficile Infection Infection Prevention Approaches for Clostridioides difficile Clostridioides difficile in Children Making Sense of Differing Guidelines for Clostridioides difficile Infection Predictive Modeling for Clostridioides difficile Infection: Current State of the Science, Clinical Applications, and Future Directions Advances in Understanding the Pathogenesis of Clostridioides difficile Infection In vitro and in Vivo Models for Understanding Clostridioides difficile Immune Aspects of Clostridioides difficile Infection and Vaccine Development
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