Description
Completely updated and revised, the 28th edition of this best-selling reference provides instant access to the latest recommendations for treatment of infectious diseases in children.
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For each disease, the authors provide a commentary to help select the best of all antimicrobial choices. Drug descriptions cover all antimicrobial agents available today and include complete information about dosing regimens.
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TOPICS INCLUDE - Antimicrobial Therapy by Clinical Syndromes
- Antimicrobial Therapy for Neonates
- Choosing Among
- Antibiotics
- Antifungal Agents
- Antiviral Agents
- Antiparasitic Agents
- Oral Step-down Therapy for Serious Infections
- Prevention of Symptomatic Infection
- Approach to Antibiotic Allergies
- Antibiotic Stewardship
New in the 28th Edition- Updated recommendations on acute hematogenous osteomyelitis, based on newly published guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America, including information on a decrease in the incidence of MRSA infections, allowing the recommendation of cefazolin, again, in empiric therapy for most pediatric bone infections
- Updated recommendations on influenza treatment and prophylaxis, reflecting American Academy of Pediatrics guidance for 2021–2022
- Ceftazidime/avibactam now preferred over fluoroquinolones for treatment of Klebsiella pneumoniae carbapenemase–producing enteric bacilli, if susceptible
- Cefiderocol, a new iron-binding siderophore cephalosporin class, recently approved in adults for treatment of many drug-resistant pathogens, particularly Acinetobacter, Stenotrophomonas, and Pseudomonas; under study in children
- New dosing for posaconazole suspension formulation
- New approaches to mucormycosis
- Added baloxavir for children 12+ years old
3. Preferred Therapy for Specific Bacterial and Mycobacterial Pathogens A. Common Bacterial Pathogens and Usual Pattern of Susceptibility to Antibiotics (Gram Positive)
B. Common Bacterial Pathogens and Usual Pattern of Susceptibility to Antibiotics (Gram Negative)C. Common Bacterial Pathogens and Usual Pattern of Susceptibility to Antibiotics (Anaerobes)D. Preferred Therapy for Specific Bacterial and Mycobacterial Pathogens4. Choosing Among Antibiotics Within a Class:: Beta-lactams and Beta-lactamase Inhibitors, Macrolides, Aminoglycosides, and Fluoroquinolones5. Preferred Therapy for Specific Fungal Pathogens A. Overview of More Common Fungal Pathogens and Their Usual Pattern of Antifungal Susceptibilities
B. Systemic Infections
C. Localized Mucocutaneous Infections6. Choosing Among Antifungal Agents:: Polyenes, Azoles, and Echinocandins7. Preferred Therapy for Specific Viral Pathogens A. Overview of Non-HIV, Non-hepatitis B or C Viral Pathogens and Usual Pattern of Susceptibility to Antivirals
B. Overview of Hepatitis B or C Viral Pathogens and Usual Pattern of Susceptibility to AntiviralsC. Preferred Therapy for Specific Viral Pathogens8. Choosing Among Antiviral Agents9. Preferred Therapy for Specific Parasitic Pathogens A. Selected Common Pathogenic Parasites and Suggested Agents for Treatment.
B. Preferred Therapy for Specific Parasitic Pathogens10. Choosing Among Antiparasitic Agents:: Antimalarial Drugs, Nitroimidazoles, Benzimidazoles, and Neglected Tropical Diseases11. How Antibiotic Dosages Are Determined Using Susceptibility Data, Pharmacodynamics, and Treatment Outcomes12. Approach to Antibiotic Therapy of Drug-Resistant Gram-negative Bacilli and Methicillin-Resistant Staphylococcus aureus13. Antibiotic Therapy for Children Who Are Obese14. Sequential Parenteral-Oral Antibiotic Therapy (Oral Step-down Therapy) for Serious Infections15. Antimicrobial Prophylaxis/Prevention of Symptomatic Infection A. Postexposure Antimicrobial Prophylaxis to Prevent Infection
B. Long-term Antimicrobial Prophylaxis to Prevent Symptomatic New InfectionC. Prophylaxis of Symptomatic Disease in Children Who Have Asymptomatic Infection/Latent InfectionD. Surgical/Procedure Prophylaxis16. Approach to Antibiotic Allergies17. Antibiotic Stewardship18. ;Systemic and Topical Antimicrobial Dosing and Dose Forms A. Systemic Antimicrobials With Dosage Forms and Usual Dosages
B. Topical Antimicrobials (Skin, Eye, Ear, Mucosa)Appendix:: Nomogram for Determining Body Surface AreaReferencesIndex