Historical Overview of Chromatography & Related Techniques in Analysis of Antimalarial Drug Primaquine

Authors:

Ilia Brondz

Brand: Nova Science Publishers Inc

ISBN: 9781617619441

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Description

Every year over one million children die from malaria in sub-Saharan Africa alone, and about 500 million new cases are registered world-wide annually. Today, malaria is not longer limited to poor areas of world, but has returned to southern European countries, such as Italy, France, and some countries in the Caucasus. Children are most vulnerable to this disease, and in Africa, childhood deaths from malaria account for about 90% of the total human deaths from this disease. Primaquine has strong anti-parasitic effects against the malarial gametocytes and therefore prevent the spread of the parasite to mosquitoes from infected patients undergoing treatment. This book examines the problems related to malaria and anti-malarial drugs.

Product Details

Brand Nova Science Publishers Inc

Reference 73611

EAN13 9781617619441

ISBN 9781617619441

Data sheet

Publication date: 2011
Issue number: 1
Cover: hard cover
Pages count: 222
Dimensions (mm): 260.00 x 180.00
Weight (g): 650

Preface; History of malaria; Discovery & introduction of natural & synthetic antimalarial drugs & agents relevant to the suppression of the malaria mosquito; Pharmacopeias:: their history & place in drug quality control; Analytical quantitative measurements; Discovery & development of chromatography; Planar chromatography or Open-bed chromatography as a tool for the qualitative & quantitative analysis of primaquine; High-performance liquid chromatography (HPLC; Supercritical fluid chromatography (SFC; Gas chromatography (GC) & gas chromatography -- mass spectroscopy; Spectroscopy & spectrometry; In search of antimalarial drugs in the 8-methoxyaminoquinoline; Whos who in the world struggle to curb malaria; The Via Dolorosa (the Way of Grief or Suffering); Index.