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Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases

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9780323482554
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Description

For four decades, physicians and other healthcare providers have trusted Mandell, Douglas, and Bennetts Principles and Practice of Infectious Diseases to provide expert guidance on the diagnosis and treatment of these complex disorders. The 9th Edition continues the tradition of excellence with newly expanded chapters, increased global coverage, and regular updates to keep you at the forefront of this vitally important field. Meticulously updated by Drs. John E. Bennett, Raphael Dolin, and Martin J. Blaser, this comprehensive, two-volume masterwork puts the latest information on challenging infectious diseases at your fingertips.

Product Details
Elsevier
62688
9780323482554
9780323482554

Data sheet

Publication date
2019
Issue number
9
Cover
hard cover
Pages count
4176
Dimensions (mm)
216 x 276
Weight (g)
8250
  • I Basic Principles in the Diagnosis and Management of Infectious Diseases
    A MICROBIAL PATHOGENESIS
    1 A Molecular Perspective of Microbial Pathogenicity
    2 The Human Microbiome of Local Body Sites and Their Unique Biology
    3 Prebiotics, Probiotics, and Synbiotics
    B HOST DEFENSE MECHANISMS
    4 Innate (General or Nonspecific) Host Defense Mechanisms
    5 Adaptive Immunity: Antibodies and Immunodeficiencies
    6 Cell-Mediated Defense Against Infection
    7 Mucosal Immunity
    8 Granulocytic Phagocytes
    9 Complement and Deficiencies
    10 Human Genetics and Infection
    11 Nutrition, Immunity, and Infection
    12 Evaluation of the Patient With Suspected Immunodeficiency
    C EPIDEMIOLOGY OF INFECTIOUS DISEASE
    13 Applied Epidemiology for the Infectious Diseases Physician
    14 Emerging and Reemerging Infectious Disease Threats
    15 Bioterrorism: An Overview
    D CLINICAL MICROBIOLOGY
    16 The Clinician and the Microbiology Laboratory: Test Ordering, Specimen Collection, and Result Interpretation
    E ANTIINFECTIVE THERAPY
    17 Principles of Antiinfective Therapy
    18 Molecular Mechanisms of Antibiotic Resistance in Bacteria
    19 Pharmacokinetics and Pharmacodynamics of Antiinfective Agents
    20 Penicillins and ß-Lactamase Inhibitors
    21 Cephalosporins
    22 Ertapenem, Imipenem, Meropenem, Doripenem, and Aztreonam
    23 Antibiotic Allergy
    24 Fusidic Acid
    25 Aminoglycosides
    26 Tetracyclines, Glycylcyclines, and Chloramphenicol
    27 Rifamycins
    28 Metronidazole
    29 Macrolides and Clindamycin
    30 Glycopeptides (Vancomycin and Teicoplanin) and Lipoglycopeptides (Telavancin, Oritavancin, and Dalbavancin)
    31 Daptomycin and Quinupristin-Dalfopristin
    32 Polymyxins (Polymyxin B and Colistin)
    33 Linezolid, Tedizolid, and Other Oxazolidinones
    34 Sulfonamides and Trimethoprim; Trimethoprim-Sulfamethoxazole
    35 Quinolones
    36 Unique Antibacterial Agents
    37 Urinary Tract Agents: Nitrofurantoin, Fosfomycin, and Methenamine
    38 Topical Antibacterials
    39 Antimycobacterial Agents
    40A Antifungal Agents: Amphotericin B
    40B Antifungal Drugs: Azoles
    40C Antifungal Drugs: Echinocandins
    40D Antifungal Drugs: Flucytosine
    41 Antimalarial Drugs
    42 Drugs for Protozoal Infections Other Than Malaria
    43 Drugs for Helminths
    44 Antiviral Agents: General Principles
    45 Antiviral Drugs for Influenza and Other Respiratory Virus Infections
    46 Antivirals Against Herpesviruses
    47 Antiviral Drugs Against Hepatitis Viruses
    48 Miscellaneous Antiviral Agents (Interferons, Tecovirimat, Imiquimod, Pocapavir, Pleconaril)
    49 Immunomodulators
    50 Hyperbaric Oxygen
    51 Antimicrobial Stewardship
    52 Designing and Interpreting Clinical Studies in Infectious Diseases
    53 Outpatient Parenteral Antimicrobial Therapy
    54 Tables of Antiinfective Agent Pharmacology
    II Major Clinical Syndromes
    A FEVER
    55 Temperature Regulation and the Pathogenesis of Fever
    56 Fever of Unknown Origin
    57 The Acutely Ill Patient With Fever and Rash
    B UPPER RESPIRATORY TRACT INFECTIONS
    58 The Common Cold
    59 Pharyngitis
    60 Acute Laryngitis
    61 Otitis Externa, Otitis Media, and Mastoiditis
    62 Sinusitis
    63 Epiglottitis
    64 Infections of the Oral Cavity, Neck, and Head
    C PLEUROPULMONARY AND BRONCHIAL INFECTIONS
    65 Acute Bronchitis
    66 Acute Exacerbations of Chronic Obstructive Pulmonary Disease
    67 Acute Pneumonia
    68 Pleural Effusion and Empyema
    69 Bacterial Lung Abscess
    70 Chronic Pneumonia
    71 Cystic Fibrosis
    D URINARY TRACT INFECTIONS
    72 Urinary Tract Infections
    E SEPSIS
    73 Sepsis and Septic Shock
    F INTRAABDOMINAL INFECTIONS
    74 Peritonitis and Intraperitoneal Abscesses
    75 Infections of the Liver and Biliary System (Liver Abscess, Cholangitis, Cholecystitis)
    76 Pancreatic Infection
    77 Splenic Abscess
    78 Appendicitis
    79 Diverticulitis and Neutropenic Enterocolitis
    G CARDIOVASCULAR INFECTIONS
    80 Endocarditis and Intravascular Infections
    81 Prosthetic Valve Endocarditis
    82 Infections of Nonvalvular Cardiovascular Devices
    83 Prevention of Infective Endocarditis
    84 Myocarditis and Pericarditis
    85 Mediastinitis
    H CENTRAL NERVOUS SYSTEM INFECTIONS
    86 Approach to the Patient With Central Nervous System Infection
    87 Acute Meningitis
    88 Chronic Meningitis
    89 Encephalitis
    90 Brain Abscess
    91 Subdural Empyema, Epidural Abscess, and Suppurative Intracranial Thrombophlebitis
    92 Cerebrospinal Fluid Shunt and Drain Infections
    I SKIN AND SOFT TISSUE INFECTIONS
    93 Cellulitis, Necrotizing Fasciitis, and Subcutaneous Tissue Infections
    94 Myositis and Myonecrosis
    95 Lymphadenitis and Lymphangitis
    J GASTROINTESTINAL INFECTIONS AND FOOD POISONING
    96 Syndromes of Enteric Infection
    97 Esophagitis
    98 Diarrhea With Little or No Fever
    99 Acute Dysentery Syndromes (Diarrhea With Fever)
    100 Typhoid Fever, Paratyphoid Fever, and Typhoidal Fevers
    101 Foodborne Disease
    102 Tropical Sprue and Environmental Enteric Dysfunction
    K BONE AND JOINT INFECTIONS
    103 Infectious Arthritis of Native Joints
    104 Osteomyelitis
    105 Orthopedic Implant-Associated Infections
    L DISEASES OF THE REPRODUCTIVE ORGANS AND SEXUALLY TRANSMITTED DISEASES
    106 Genital Skin and Mucous Membrane Lesions
    107 Urethritis
    108 Vulvovaginitis and Cervicitis
    109 Infections of the Female Pelvis
    110 Prostatitis, Epididymitis, and Orchitis
    M EYE INFECTIONS
    111 Introduction to Eye Infections
    112 Microbial Conjunctivitis
    113 Microbial Keratitis
    114 Endophthalmitis
    115 Infectious Causes of Uveitis
    116 Periocular Infections
    N HEPATITIS
    117 Viral Hepatitis
    O ACQUIRED IMMUNODEFICIENCY SYNDROME
    118 Global Perspectives on Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome
    119 Epidemiology and Prevention of AIDS and HIV Infection, Including Preexposure Prophylaxis and HIV Vaccine Development
    120 Diagnosis of Human Immunodeficiency Virus Infection
    121 The Immunology of Human Immunodeficiency Virus Infection
    122 General Clinical Manifestations of Human Immunodeficiency Virus Infection (Including Acute Retroviral Syndrome and Oral, Cutaneous, Renal, Ocular, Metabolic, and Cardiac Diseases)
    123 Pulmonary Manifestations of Human Immunodeficiency Virus Infection
    124 Gastrointestinal, Hepatobiliary, and Pancreatic Manifestations of Human Immunodeficiency Virus Infection
    125 Neurologic Diseases Caused by Human Immunodeficiency Virus Type 1 and Opportunistic Infections
    126 Human Immunodeficiency Virus Infection in Women
    127 Pediatric Human Immunodeficiency Virus Infection
    128 Antiretroviral Therapy for Human Immunodeficiency Virus Infection
    129 Management of Opportunistic Infections Associated With Human Immunodeficiency Virus Infection
    P MISCELLANEOUS SYNDROMES
    130 Chronic Fatigue Syndrome (Systemic Exertion Intolerance Disease)
    III Infectious Diseases and Their Etiologic Agents
    A VIRAL DISEASES
    131 Biology of Viruses and Viral Diseases
    132 Orthopoxviruses Vaccinia (Smallpox Vaccine), Variola (Smallpox), Monkeypox, and Cowpox
    133 Other Poxviruses That Infect Humans: Parapoxviruses (Including Orf Virus), Molluscum Contagiosum, and Yatapoxviruses
    134 Introduction to Herpesviridae
    135 Herpes Simplex Virus
    136 Chickenpox and Herpes Zoster (Varicella-Zoster Virus)
    137 Cytomegalovirus
    138 Epstein-Barr Virus (Infectious Mononucleosis, Epstein-Barr Virus-Associated Malignant Diseases, and Other Diseases)
    139 Human Herpesvirus Types 6 and 7 (Exanthem Subitum)
    140 Kaposi Sarcoma-Associated Herpesvirus (Human Herpesvirus 8)
    141 Herpes B Virus
    142 Adenoviruses
    143 Papillomaviruses
    144 JC, BK, and Other Polyomaviruses: Progressive Multifocal Leukoencephalopathy (PML)
    145 Hepatitis B Virus
    146 Hepatitis Delta Virus
    147 Human Parvoviruses, Including Parvovirus B19V and Human Bocaparvoviruses
    148 Orthoreoviruses and Orbiviruses
    149 Coltiviruses (Colorado Tick Fever Virus) and Seadornaviruses
    150 Rotaviruses
    151 Alphaviruses (Chikungunya, Eastern Equine Encephalitis)
    152 Rubella Virus (German Measles)
    153 Flaviviruses (Dengue, Yellow Fever, Japanese Encephalitis, West Nile Encephalitis, Usutu Encephalitis, St. Louis Encephalitis, Tick-Borne Encephalitis, Kyasanur Forest Disease, Alkhurma Hemorrhagic Fever, Zika)
    154 Hepatitis C
    155 Coronaviruses, Including Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS)
    156 Parainfluenza Viruses
    157 Mumps Virus
    158 Respiratory Syncytial Virus
    159 Human Metapneumovirus
    160 Measles Virus (Rubeola)
    161 Zoonotic Paramyxoviruses: Nipah, Hendra, and Menangle Viruses
    162 Vesicular Stomatitis Virus and Related Vesiculoviruses (Chandipura Virus)
    163 Rabies (Rhabdoviruses)
    164 Marburg and Ebola Virus Hemorrhagic Fevers
    165 Influenza Viruses, Including Avian Influenza and Swine Influenza
    166 California Encephalitis, Hantavirus Pulmonary Syndrome, Hantavirus Hemorrhagic Fever With Renal Syndrome, and Bunyavirus Hemorrhagic Fevers
    167 Lymphocytic Choriomeningitis Virus, Lassa Virus, and the South American Hemorrhagic Fevers (Arenaviruses)
    168 Human T-Cell Leukemia Viruses (HTLV-1, HTLV-2)
    169 Human Immunodeficiency Viruses
    170 Introduction to the Human Enteroviruses and Parechoviruses
    171 Poliovirus
    172 Coxsackieviruses, Echoviruses, and Numbered Enteroviruses (EV-A71, EVD-68, EVD-70)
    173 Parechoviruses
    174 Hepatitis A Virus
    175 Rhinovirus
    176 Noroviruses and Sapoviruses (Caliciviruses)
    177 Astroviruses and Picobirnaviruses
    178 Hepatitis E Virus
    B PRION DISEASES
    179 Prions and Prion Disease of the Central Nervous System (Transmissible Neurodegenerative Diseases)
    C CHLAMYDIAL DISEASES
    180 Chlamydia trachomatis (Trachoma and Urogenital Infections)
    181 Psittacosis (Due to Chlamydia psittaci)
    182 Chlamydia pneumoniae
    D MYCOPLASMA DISEASES
    183 Mycoplasma pneumoniae and Atypical Pneumonia
    184 Genital Mycoplasmas: Mycoplasma genitalium, Mycoplasma hominis, and Ureaplasma Species
    E RICKETTSIOSES, EHRLICHIOSES, AND ANAPLASMOSES
    185 Introduction to Rickettsioses, Ehrlichioses, and Anaplasmoses
    186 Rickettsia rickettsii and Other Spotted Fever Group Rickettsiae (Rocky Mountain Spotted Fever and Other Spotted Fevers)
    187 Rickettsia akari (Rickettsialpox)
    188 Coxiella burnetii (Q Fever)
    189 Rickettsia prowazekii (Epidemic or Louse-Borne Typhus)
    190 Rickettsia typhi (Murine Typhus)
    191 Orientia tsutsugamushi (Scrub Typhus)
    192 Ehrlichia chaffeensis (Human Monocytotropic Ehrlichiosis), Anaplasma phagocytophilum (Human Granulocytotropic Anaplasmosis), and Other Anaplasmataceae
    F BACTERIAL DISEASES
    193 Introduction to Bacteria and Bacterial Diseases
    194 Staphylococcus aureus (Including Staphylococcal Toxic Shock Syndrome)
    195 Staphylococcus epidermidis and Other Coagulase-Negative Staphylococci
    196 Classification of Streptococci
    197 Streptococcus pyogenes
    198 Nonsuppurative Poststreptococcal Sequelae: Rheumatic Fever and Glomerulonephritis
    199 Streptococcus pneumoniae
    200 Enterococcus Species, Streptococcus gallolyticus Group, and Leuconostoc Species
    201 Streptococcus agalactiae (Group B Streptococci)
    202 Viridans Streptococci, Nutritionally Variant Streptococci, and Groups C and G Streptococci
    203 Streptococcus anginosus Group
    204 Corynebacterium diphtheriae (Diphtheria)
    205 Other Coryneform Bacteria, Arcanobacterium haemolyticum, and Rhodococci
    206 Listeria monocytogenes
    207 Bacillus anthracis (Anthrax)
    208 Bacillus Species and Related Genera Other Than Bacillus anthracis
    209 Erysipelothrix Rhusiopathiae
    210 Whipple Disease
    211 Neisseria meningitidis
    212 Neisseria gonorrhoeae (Gonorrhea)
    213 Moraxella catarrhalis, Kingella, and Other Gram-Negative Cocci
    214 Vibrio cholerae
    215 Other Pathogenic Vibrios
    216 Campylobacter jejuni and Related Species
    217 Helicobacter pylori and Other Gastric Helicobacter Species
    218 Enterobacteriaceae
    219 Pseudomonas aeruginosa and Other Pseudomonas Species
    220 Stenotrophomonas maltophilia and Burkholderia cepacia Complex
    221 Burkholderia pseudomallei and Burkholderia mallei: Melioidosis and Glanders
    222 Acinetobacter Species
    223 Salmonella Species
    224 Bacillary Dysentery: Shigella and Enteroinvasive Escherichia coli
    225 Haemophilus Species, Including H. influenzae and H. ducreyi (Chancroid)
    226 Brucellosis (Brucella Species)
    227 Francisella tularensis (Tularemia)
    228 Pasteurella Species
    229A Plague (Yersinia pestis)
    229B Yersinia enterocolitica and Yersinia pseudotuberculosis
    230 Bordetella pertussis
    231 Rat-Bite Fever: Streptobacillus moniliformis and Spirillum minus
    232 Legionnaires Disease and Pontiac Fever
    233 Capnocytophaga
    234 Bartonella, Including Cat-Scratch Disease
    235 Klebsiella granulomatis (Donovanosis, Granuloma Inguinale)
    236 Other Gram-Negative and Gram-Variable Bacilli
    237 Syphilis (Treponema pallidum)
    238 Endemic Treponematoses
    239 Leptospira Species (Leptospirosis)
    240 Relapsing Fever Caused by Borrelia Species
    241 Lyme Disease (Lyme Borreliosis) Due to Borrelia burgdorferi
    242 Anaerobic Infections: General Concepts
    243 Clostridioides difficile (Formerly Clostridium difficile) Infection
    244 Tetanus (Clostridium tetani)
    245 Botulism (Clostridium botulinum)
    246 Diseases Caused by Clostridium
    247 Bacteroides, Prevotella, Porphyromonas, and Fusobacterium Species (and Other Medically Important Anaerobic Gram-Negative Bacilli)
    248 Anaerobic Cocci and Anaerobic Gram-Positive Nonsporulating Bacilli
    249 Mycobacterium tuberculosis
    250 Leprosy (Mycobacterium leprae)
    251 Mycobacterium avium Complex
    252 Infections Caused by Nontuberculous Mycobacteria Other Than Mycobacterium avium Complex
    253 Nocardia Species
    254 Agents of Actinomycosis
    G MYCOSES
    255 Introduction to Mycoses
    256 Candida Species
    257 Aspergillus Species
    258 Agents of Mucormycosis and Entomophthoramycosis
    259 Sporothrix schenckii
    260 Agents of Chromoblastomycosis
    261 Agents of Mycetoma
    262 Cryptococcosis (Cryptococcus neoformans and Cryptococcus gattii)
    263 Histoplasma capsulatum (Histoplasmosis)
    264 Blastomycosis
    265 Coccidioidomycosis (Coccidioides Species)
    266 Dermatophytosis (Ringworm) and Other Superficial Mycoses
    267 Paracoccidioidomycosis
    268 Uncommon Fungi and Related Species
    269 Pneumocystis Species
    270 Microsporidiosis
    H PROTOZOAL DISEASES
    271 Introduction to Protozoal Diseases
    272 Entamoeba Species, Including Amebic Colitis and Liver Abscess
    273 Free-Living Amebae
    274 Malaria (Plasmodium Species)
    275 Leishmania Species: Visceral (Kala-Azar), Cutaneous, and Mucosal Leishmaniasis
    276 Trypanosoma Species (American Trypanosomiasis, Chagas Disease): Biology of Trypanosomes
    277 Agents of African Trypanosomiasis (Sleeping Sickness)
    278 Toxoplasma gondii
    279 Giardia lamblia
    280 Trichomonas vaginalis
    281 Babesia Species
    282 Cryptosporidiosis (Cryptosporidium Species)
    283 Cyclospora cayetanensis, Cystoisospora belli, Sarcocystis Species, Balantidium coli, and Blastocystis Species
    I DISEASES DUE TO TOXIC ALGAE
    284 Human Illness Associated With Harmful Algal Blooms
    J DISEASES DUE TO HELMINTHS
    285 Introduction to Helminth Infections
    286 Intestinal Nematodes (Roundworms)
    287 Tissue Nematodes, Including Trichinellosis, Dracunculiasis, Filariasis, Loiasis, and Onchocerciasis
    288 Trematodes (Schistosomes and Liver, Intestinal, and Lung Flukes)
    289 Tapeworms (Cestodes)
    290 Visceral Larva Migrans and Other Uncommon Helminth Infections
    K ECTOPARASITIC DISEASES
    291 Introduction to Ectoparasitic Diseases
    292 Lice (Pediculosis)
    293 Scabies
    294 Myiasis and Tungiasis
    295 Mites, Including Chiggers
    296 Ticks, Including Tick Paralysis
    L DISEASES OF UNKNOWN ETIOLOGY
    297 Kawasaki Disease
    IV Special Problems
    A NOSOCOMIAL INFECTIONS
    298 Infection Prevention and Control in the Health Care Setting
    299 Disinfection, Sterilization, and Control of Hospital Waste
    300 Infections Caused by Percutaneous Intravascular Devices
    301 Nosocomial Pneumonia
    302 Health Care-Associated Urinary Tract Infections
    303 Health Care-Acquired Hepatitis
    304 Transfusion- and Transplantation-Transmitted Infections
    B INFECTIONS IN SPECIAL HOSTS
    305 Infections in the Immunocompromised Host: General Principles
    306 Prophylaxis and Empirical Therapy of Infection in Cancer Patients
    307 Infections in Recipients of Hematopoietic Stem Cell Transplants
    308 Infections in Solid-Organ Transplant Recipients
    309 Infections in Patients With Spinal Cord Injury
    310 nfections in Older Adults
    311 Infections in Asplenic Patients
    312 Infections in Injection Drug Users
    313 Surgical Site Infections and Antimicrobial Prophylaxis
    C SURGICAL- AND TRAUMA-RELATED INFECTIONS
    314 Burns
    315 Bites
    D IMMUNIZATION
    316 Immunization
    E ZOONOSES
    317 Zoonoses
    F PROTECTION OF TRAVELERS
    318 Protection of Travelers
    319 Infections in Returning Travelers
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