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Autoimmune Disorders: Adjuvants and Other Risk Factors in Pathogenesis

Autoimmune Disorders: Adjuvants and Other Risk Factors in Pathogenesis

9781119858416
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Description

Comprehensive resource on the science of autoimmune disorders, covering causes, treatment, prevention, and the latest research in the field

Autoimmune Disorders is an authoritative reference on the science of autoimmune disorders, covering their causes, including infections, vaccine adjuvants, environmental stimuli, and silicone implants, the latest research on the genetics, epigenetics, and immunology of autoimmunity, predictive markers, therapeutic approaches for treatment and prevention, and suggestions for future research directions.

This book explores the intricate connections between adjuvants and autoimmune responses, focusing on the emergence of the Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA syndrome), as well as autoimmune connections in areas such as chronic fatigue syndrome, autoantibodies targeting the autonomic system, and small fiber neuropathy. The authors emphasize the profound impact of vaccines on public health, underscoring that their benefits far outweigh potential side effects and exploring the historical context of adjuvants in vaccine development. From tattoos to environmental factors, each chapter adds a unique thread to the tapestry of adjuvants, autoimmune responses, and their interactions.

Sample topics covered in Autoimmune Disorders include::

  • Food additives and dental implants as a trigger of autoimmunity and increased risk of ASIA syndrome as a result of the chemical and social factors
  • Sustained immune activation in ASIA syndrome as a bridge to lymphomagenesis and how immune checkpoints, metals, and bisphenol connect to autoimmunity
  • Postural Orthostatic Tachycardia syndrome (POTS), Sick Building syndrome, and Gulf War syndrome (GWS) as parts of ASIA syndrome
  • Sarcoidosis and Sjögren’s syndrome as a proof of concept of hyperstimulation syndrome

Autoimmune Disorders is an essential reference on the subject for academics, specialized postgraduate students, and practicing professionals seeking to improve integrated research strategies and foster a deeper understanding of the complex relationship between immunology, public health, and individual well-being.

Product Details
Wiley-Blackwell
101495
9781119858416

Data sheet

Publication date
2024
Issue number
1
Cover
hard cover
Pages count
368
Dimensions (mm)
190.00 x 255.00

  • List of Contributors vii

    Introduction xiii
    Abdulla Watad, Nicola Luigi Bragazzi, and Yehuda Sheonfeld

    1 Hyperstimulation of the Immune System 1
    Hadas Hodadov and Abdulla Watad

    2 Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA): Genetics, Immunization, and Autoimmunity 7
    Carlo Perricone, Elena Bartoloni Bocci, and Roberto Gerli

    3 Vaccine Adjuvants: History, Role, Mechanisms of Action, and Side Effects 15
    Nicola Luigi Bragazzi, Abdulla Watad, and Yehuda Shoenfeld

    4 Commonly Used Food Additives Are Nutritional Adjuvants in ASIA Syndrome 29
    Aaron Lerner and Carina Benzvi

    5 Silicone Implant Incompatibility Syndrome 51
    Vânia Borba and Yehuda Shoenfeld

    7 Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA or Shoenfeld’s Syndrome) Due to Polypropylene Mesh Implants 67
    Jan Willem Cohen Tervaert and Mohammed Osman

    8 Vaccines, Vaccinosis, and Autoimmunity 85
    Nicola Luigi Bragazzi, Abdulla Watad, and Yehuda Shoenfeld

    9 Sustained Immune Activation in ASIA Syndrome – A Bridge to Lymphomagenesis 91
    Dana Butnaru

    10 Chronic Fatigue Syndrome 107
    Kassem Sharif

    11 Autoantibodies and Autonomic Nervous System 117
    Iana Leineman, Varvara Ryabkova, and Natalia Gavrilova

    12 Postural Orthostatic Tachycardia Syndrome (POTS) as a Part of ASIA Syndrome 129
    Paula David

    6 Silicone Breast Implants (SBIs) and Autoimmune Dysautonomya 63
    Gilad Halpert, Abdulla Watad, Howard Amital, and Yehuda Shoenfeld

    13 Role of the Small-fiber Neuropathy in the Pathogenesis of ASIA Syndrome 137
    N. Gavrilova, E. Kamaeva, M. Lukashenko, and L. Soprun

    14 Tattoo as a Possible Trigger for Autoimmune Syndrome Induced by Adjuvants 147
    Paula David

    15 The Sick Building Syndrome as a Part of the Autoimmune (Autoinflammatory) Syndrome Induced by Adjuvant 155
    Asher Pardo and Eitan Israeli

    22 Sjögren’s Syndrome as a Proof of Concept of the Hyperstimulation Syndrome 265
    Vânia Borba and Yehuda Shoenfeld

    23 Gluteal Biopolymer Injections as a Case of ASIA Syndrome 283
    Rojas-Villarraga Adriana, María Alejandra Martínez-Ceballos, Uribe Rosa, and Montealegre Giovanni

    16 Gulf War Syndrome (GWS) and ASIA Syndrome 167
    Efrosiniia Talalai

    17 Vaccinations in Patients with Autoimmune Diseases 181
    Isa Seida and Naim Mahroum

    18 Autoimmune Phenomena in Cancer Patients Treated with Immune Checkpoint Inhibitors 191
    Milena Tocut, Michael Ehrenfeld, and Gisele Zandman-Goddard

    19 Heavy Metals in Autoimmune Diseases: Too Much Noise in Autoimmunity 201
    Kassem Sharif and Howard Amital

    20 The Role of Bisphenol A in ASIA Syndrome 225
    Zora Lazurova

    21 Sarcoidosis and Autoimmune Inflammatory Syndrome Induced by Adjuvants: Is There a Connection? 247
    Anna Malkova, Yulia Zinchenko, Anna Starshinova, Igor Kudryavtsev, Piotr Yablonskiy, and Yehuda Shoenfeld

    24 The Chemical and Social Landscape of the Modern World and Increased Risk of ASIA 305
    Albert Pinhasov, Elena Shmerkin, and Michael Kirby

    25 Oil Injections and ASIA Syndrome 323
    Olga Vera-Lastra, Alberto Ordinola-Navarro, Abihai Lucas Hernández, Gabriela Medina, María P. Cruz-Domínguez, Gabriel M. Ramírez, and Luis J. Jara

    26 Metals in Dental Implants as a Trigger of Autoimmunity 337
    Arad Dotan and Yehuda Shoenfeld

    27 Conclusions: State of the Art and Prospects 341
    Abdulla Watad, Nicola Luigi Bragazzi, and Yehuda Shoenfeld

    Index 345

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