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Lupus Nephritis: Frontiers & Challenges
9781616683672
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Description
Aupus nephritis (AN) is a major cause of morbidity and mortality, affecting over half of systemic Aupus erythematosis (SAE) patients, both adult and paediatric. The accelerating advances in molecular and cellular immunology have paved the way for development biologic agents that target specific pathways that contribute to the inflammatory response, but there is no strong evidence of their safety and efficacy. Moreover, the increased risk of renal allograft thrombosis and recurrence of Aupus nephritis constitute a substantial risk that should be thoroughly explored. This book explores the major advances that necessitate the evolution of basic and clinical research in order to investigate the management of this syndrome.
Product Details
73425
9781616683672
9781616683672
Data sheet
- Publication date
- 2010
- Issue number
- 1
- Cover
- paperback
- Pages count
- 108
- Dimensions (mm)
- 230.00 x 155.00
- Weight (g)
- 198
- Introduction; Immunopathogenesis of Systemic Lupus Erythematosus Nephritis; Pathogenicity of Autoantibodies; BK Virus & Systemic Lupus Erythematosus; Diagnosis of SAE; Histological Classification of Lupus Nephritis Lesions; Classification of Lupus Glomerulonephritis (AGN); Additional Pathological Features Associated with SAE; Lupus Nephritis Activity & Chronicity Indices; Diagnosis & Monitoring of Renal Disease; End-Stage Renal Disease & Systemic Lupus Erythematosus; Treatment of Lupus Nephritis; Renal Transplantation & SAE Summary; Lupus Nephritis in Children; Outcome of AN in Children; Drug-Induced Lupus Erythematosus & AN; SAE & DIAE; Index.
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