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Hematology e-dition

Text with Continually Updated Online Reference

9780443066627
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Description
The fourth edition of this leading text reflects the new direction and growth of the field of haematology as an academic and clinical discipline. Edited and written by practitioners who are the leaders of the field, the book covers both the basic scientific foundations of haematology and its clinical aspects. It provides practitioners with the most comprehensive, authoritative, up-to-date information in haematology. The table of contents has been thoroughly revised with many new chapters added, reflecting the rapidly changing nature of the molecular and cellular areas of the specialty. This definitive resource is the one comprehensive book needed by every practicing haematologist.

This e-dition includes the 2-volume 4th edition PLUS access to www.hemtext.com, where youll find the fully searchable contents of the book, weekly updates to content and much more!
Product Details
Churchill Livingstone
33022
9780443066627
9780443066627

Data sheet

Publication date
2005
Issue number
4
Dimensions (mm)
216 x 276
Weight (g)
5970
  • Part I. MOLECULAR AND CELLULAR BASIS OF HEMATOLOGY
    Chapter 1: Anatomy and Physiology of the Gene
    Chapter 2: Genomic Approaches to the Study of Hematologic Science
    Chapter 3: Protein Synthesis, Processing, and Degradation
    Chapter 4: Protein Architecture: Relationship of Form and Function
    Chapter 5: Regulation of Cellular Response
    Chapter 6: Cell Adhesion
    Chapter 7: Control of Cell Division
    Chapter 8: Cell Death
    Chapter 9: Pharmacogenomics and Hematological Diseases
    Part II. IMMUNOLOGIC BASIS OF HEMATOLOGY
    Chapter 10: Overview and Compartmentalization of the Immune System
    Chapter 11: B-Cell Development
    Chapter 12: T-Cell and NK-Cell Immunity
    Chapter 13: Dendritic Cell Biology
    Chapter 14: Regulation of Activation of B and I Lymphocytes
    Chapter 15: Leukocyte Trafficking
    Chapter 16: Tolerance and Autoimmunity
    Part III. BIOLOGY OF STEM CELLS AND DISORDERS OF HEMATOPOIESIS
    Chapter 17: Stem Cell Model of Hematopoiesis
    Chapter 18: Bone Marrow Microenvironment
    Chapter 19: The Humeral Regulation of Hematopoiesis
    Chapter 20: Biology of Erythropoiesis, Erythroid Differentiation, and Maturation
    Chapter 21: Granulopoiesis and Monocytopoiesis
    Chapter 22: Thrombocytopoiesis
    Chapter 23: Thrombocytopenia Due to Decreased Platelet Production
    Chapter 24: Inherited Forms of Bone Marrow Failure
    Chapter 25: Aplastic Anemia
    Chapter 26: Paroxysmal Nocturnal Hemoglobinuria
    Chapter 27: Pure Red Cell Aplasia
    Part IV. RED BLOOD CELLS
    Chapter 28: Pathobiology of the Human Erythrocyte and Its Hemoglobins
    Chapter 29: Approach to Anemia in the Adult and Child
    Chapter 30: Anemia of Chronic Diseases
    Chapter 31: Pathology of Iron Metabolism
    Chapter 32: Disorders of Iron Metabolism: Iron Deficiency and Overload
    Chapter 33: Heme Biosynthesis and Its Disorders: Porphyrias and Sideroblastic Anemias
    Chapter 34: Megablastic Anemias
    Chapter 35: Thalassemia Syndromes
    Chapter 36: Pathology of Sickle Cell Disease
    Chapter 37: Sickle Cell Disease
    Chapter 38: Hemoglobin Variants Associated with Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias
    Chapter 39: Red Cell Enzymopathies
    Chapter 40: Red Cell Membrane Disorders
    Chapter 41: Autoimmune Hemolytic Anemias
    Chapter 42: Extrinsic Nonimmune Hemolytic Anemias
    Part V. HOST DEFENSE AND ITS DISORDERS
    Chapter 43: Complement Biology and Immunoglobulin
    Chapter 44: Normal Phagocyte Structure and Function
    Chapter 45: Eosinophilia, Eosinophil-Associated Diseases, Chronic Eosinophil Leukemia, and the Hypereosinophilic Syndromes
    Chapter 46: Disorders of Phagocyte Function and Number
    Chapter 47: Disorders of Lymphocyte Function
    Chapter 48: Histiocytic Disorders
    Chapter 49: Lysosomal Storage Diseases: Perspective and Principles
    Chapter 50 Infectious Mononucleosis and Other Epstein-Barr Virus-Associated Diseases
    Chapter 51: The Spleen and Its Disorders
    Chapter 52: Basophils, Mast Cells, and Systemic Mastocytosis
    Part VI. HEMATOLOGIC MALIGNANCIES
    Chapter 53: Conventional Cytogenetics and Molecular Cytogenetics in Hematological Malignancies
    Chapter 54: The Molecular Basis of Neoplasia
    Chapter 55: Pharmacology and Molecular Mechanisms of Antineoplastic Agents for Hematologic Malignancies
    Chapter 56: Radiation Therapy in the Treatment of Hematologic Malignancies
    Chapter 57: Clinical Use of Hematopoietic Growth Factors
    Chapter 58: Radioimmunotherapy for B-Cell and Non-Hodgkin Lymphoma
    Chapter 59: Pathobiology of Acute Myeloid Leukemia
    Chapter 60: Clinical Manifestations of Acute Myeloid Leukemia
    Chapter 61: Therapy for Acute Myeloid Leukemia
    Chapter 62: Acute Myeloid Leukemia in Children
    Chapter 63: Pathobiology of Acute Lymphoblastic Leukemia
    Chapter 64: Clinical Manifestations of Acute Lymphoblastic Leukemia
    Chapter 65: Treatment of Childhood Acute Lymphoblastic Leukemia
    Chapter 66: Acute Lymphoblastic Leukemia in Adults
    Chapter 67: Myelodysplastic Syndrome: Biology and Treatment
    Chapter 68: Polycythemia Vera
    Chapter 69: Chronic Myeloid Leukemia
    Chapter 70: Myelofibrosis with Myeloid Metaplasia
    Chapter 71: Essential Thrombocythemia
    Chapter 72: Myelodysplastic Syndromes and Myeloproliferative Syndromes in Children
    Chapter 73: Pathobiology of Non-Hodgkin Lymphomas
    Chapter 74: Patho-Biology of Hodgkins Lymphoma
    Chapter 75: Hodgkins Disease: Clinical Manifestations, Staging, and Therapy
    Chapter 76: The Pathologic Basis for the Classification of Non-Hodgkin Lymphomas
    Chapter 77: Clinical Manifestations, Staging, and Treatment of Non-Hodgkin Lymphoma
    Chapter 78: Malignant Lymphomas in Childhood
    Chapter 79: Chronic Lymphocytic Leukemia
    Chapter 80: Hairy Cell Leukemia
    Chapter 81: Cutaneous T-Cell Lymphomas
    Chapter 82: AIDS-Related Lymphomas
    Chapter 83: Multiple Myeloma and Other Plasma Cell Disorders
    Chapter 84: Immunoglobulin Light Chain Amyloidosis (Primary Amyloidosis, AL)
    Chapter 85: Atypical Immune Lymphoproliferations
    Chapter 86: Clinical Approaches to Infections in the Compromised Host
    Chapter 87: Nutritional Support of Patients with Hematologic Malignancies
    Chapter 88: Psychosocial Aspects of Hematologic Disorders
    Chapter 89: Pain Management and Antiemetic Therapy in Hematologic Disorders
    Chapter 90: Palliative Care
    Chapter 91: Indwelling Access Devices
    Chapter 92: Late Complications of Hematologic Diseases and Their Therapies
    Part VII. TRANSPLANTATION
    Chapter 93: Hematopoietic Stem Cell Transplantation for Acquired Nonmalignant Diseases and Myelodysplastic Syndrome
    Chapter 94: Hematopoietic Cell Transplant for Immune Deficiences and Genetic Diseases
    Chapter 95: Results of Allogeneic Hematopoietic Cell Transplant for Hematologic Malignancies
    Chapter 96: Autologous Transplant for Hematologic malignancies and Solio Tumors
    Chapter 97: Unrelated Donor Stem Cell Transplantation Therapy Anasetti
    Chapter 98: Umbilical Cord Blood Transplantation
    Chapter 99: Preparative Regimens for Hematopoietic Cell Transplantation
    Chapter 100: Graft-versus-Host Disease and Graft-versus-Leukemia
    Chapter 101: Graft Engineering to Enhance Engraftment, Reduce Graft-versus-Host Disease and Provide a Graft-versus-Tumor Effect
    Chapter 102: Gene Transfer for Hematologic Disorders
    Chapter 103: Experimental Cell Therapy
    Chapter 104: Complications After Hematopoietic Cell Transplantation
    Part VIII. HEMOSTASIS AND THROMBOSIS
    Chapter 105: Megakaryocyte and Platelet Structure
    Chapter 106: The Molecular Basis for Platelet Function
    Chapter 107: The Molecular Basis for Platelet Activation
    Chapter 108: The Blood Vessel Wall
    Chapter 109: Molecular Basis of Blood Coagulation
    Chapter 110: Molecular and Cellular Basis of Fibrinolysis
    Chapter 111: Regulatory Mechanisms in Hemostasis: Natural Anticoagulants
    Chapter 112: Clinical Evaluation of Hemorrhagic Disorders: Bleeding History and Differential Diagnosis of Pupura
    Chapter 113: Laboratory Evaluation of Hemostatic Disorders
    Chapter 114: Structure, Biology, and Genetics of Factor VIII
    Chapter 115: Biochemistry of Factor IX and Molecular Biology of Hemophilia B
    Chapter 116: Clinical Aspects and Therapy of Hemophilia
    Chapter 117: Inhibitors in Hemophilia
    Chapter 118: Other Clotting Factor Deficiencies
    Chapter 119: Disorders of Fibrinogen
    Chapter 120: Structure, Biology, and Genetics of von Willebrand Factor
    Chapter 121: von Willebrand Disease: Clinical Aspects and Therapy
    Chapter 122: Vitamin K: Metabolism and Disorders
    Chapter 123: Inhibitors of Blood Coagulation
    Chapter 124: Disseminated Intrvascular Coagulation
    Chapter 125: Hemostatic Defects Associated with Dysproteinemias
    Chapter 126: Disorders of Coagulation in the Neonate
    Chapter 127: Hypercoagulable States
    Chapter 128: Venous Thromboembolism
    Chapter 129: Arterial Thromboembolism
    Chapter 130: Anticoagulation and Thrombolytic Therapy
    Chapter 131: Immune Thrombocytopenic Purpura, Neonatal Alloimmune Thrombocytopenia, and Posttransfusion Purpura
    Chapter 132: Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndrome
    Chapter 133: Thrombocytopenia Due to Platelet Destruction and Hypersplenism
    Chapter 134: Hereditary Disorders of Platelet Function
    Chapter 135: Acquired Disorders of Platelet Function
    Part IX. TRANSFUSION MEDICINE
    Chapter 136: Human Blood Group Anitgens and Antibodies - Part 1: Carbohydrate Determinants - Part 2: Protein Determinants
    Chapter 137: Human Platelet Antigens
    Chapter 138: Human Leukocyte Antigen (HLA) and Human Neutrophil Antigen (HNA) Systems
    Chapter 139: Principles of Red Blood Cell Transfusion
    Chapter 140: Principles of Platelet Transfusion Therapy
    Chapter 141: Principles of Neutrophil (Granulocyte) Transfusions
    Chapter 142: Transfusion of Plasma Derivatives: Fresh-Frozen Plasma, Cryoprecipitate, Albumin, and Immunoglobulins
    Chapter 143: Preparation of Plasma-Derived and Recombinant Human Plasma Proteins
    Chapter 144: Transfusion Therapy for Coagulation factor Deficiencies
    Chapter 145: Hemapheresis and Cellular Therapy
    Chapter 146: Practical Aspects of Stem Cell Collection
    Chapter 147: Transfusion Reactions
    Chapter 148: Transfusion-Transmitted Diseases
    Chapter 149: Transfusion Medicine in Hematopoietic Stem Cell and Solid Organ Transplantation
    Chapter 150: Red Blood Cell Substitutes
    Part X. CONSULTATIVE HEMATOLOGY
    Chapter 151: Hematologic Manifestations of Systemic Disease: Liver and Renal Disease
    Chapter 152: Hematologic Manifestations of Systemic Disease: Infection, Chronic Inflammation, and Cancer
    Chapter 153: Hematologic Manifestations of AIDS
    Chapter 154: Hematologic Problems in the Surgical Patient: Bleeding and Thrombosis
    Chapter 155: Hematologic Aspects of Pregnancy
    Chapter 156: Hematologic Manifestations of Childhood Illness
    Part XI. SPECIAL TESTS AND PROCEDURES
    Chapter 157: Bone Marrow Examination
    Chapter 158: Automated Analysis of Blood Cells
    Chapter 159: Laboratory Detection of Hemoglobinopathies and Thalassemias
    Chapter 160: Antenatal Diagnosis of Hematologic Disorders
    Chapter 161: Use of Molecular Techniques in the Analysis of Hematologic Diseases
    Chapter 162: Molecular Imaging in Hematology
    Appendix - Normal Blood Values: Selected Reference Values for Neonatal, Pediatric, and Adult Populations
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