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Gynaecological Cancers: Biology and Therapeutics
9781906985448
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Description
Gynaecological cancers are categorised as rare diseases, although collectively they affect over 16,000 women each year in the UK alone. There is a lack of real understanding of these conditions compared with other malignancies, possibly owing to their relative rarity when viewed as individual diseases. The 60th RCOG Study Group brought together a range of experts to examine as many biological aspects of gynaecological cancers as possible, including both surgical and non-surgical therapies. This book presents the findings of the Study Group, with contents including:: • current understanding of the biology of gynaecological cancers • translation of biology to the clinic • state of the art in imaging and therapy • current clinical trials • advances in multimodal therapy • individualised treatment.
Product Details
65843
9781906985448
9781906985448
Data sheet
- Publication date
- 2011
- Issue number
- 1
- Cover
- paperback
- Pages count
- 272
- Dimensions (mm)
- 156.00 x 234.00
- Weight (g)
- 420
- Part I. Biology of Gynaecological Cancers:: Our Current Understanding:: 1. Morphological sub-types of ovarian carcinoma:: new developments and pathogenesis W. Glenn McCluggage; 2. Novel treatment strategies for targeting genetic changes in endometrial cancer Susana Banerjee; 3. Epigenetic biomarkers in ovarian cancer Robert Brown and Janet Graham; 4. Predictive biology of ovarian cancer Christine A. Parkinson and James D. Brenton; Part II. The Translation of Biology to the Clinic:: 5. Biology of BRCA1 and BRCA2 genes and implications for cancer management Timothy A. Yap, Yvette Drew and Susan Shanley; 6. Implications of homologous recombination defectiveness in ovarian cancer Richard J. Edmondson, Asima Mukhopadhyay, Aiste Cerbinskaite and Nicola J. Curtin; 7. The future of PARP inhibitors in the treatment of cancer Yvette Drew, Timothy A. Yap and Stan B. Kaye; Part III. Imaging and Therapy:: State of the Art:: 8. The role of robotics and the future Tim Mould; 9. Ultra-radical surgery in advanced ovarian cancer Oliver Zivanovic and Dennis S. Chi; 10. Antivascular therapy in gynaecological cancers Leena Mukherjee and Gordon Rustin; 11. Oncolytic viral gene therapy in ovarian cancer Iain A. McNeish; 12. Endometrial cancer:: what have the clinical trials taught us? Andrew Clamp; 13. Targeting therapies in cancer:: opportunities in ovarian cancer Ahmed Ashour Ahmed, Stefan Knapp, Anil K. Sood and Robert C. Bast Jr; 14. Functional imaging:: from tumour biology to the clinic Nandita M. deSouza, Evis Sala, Stavroula Kyriazi and Andrea Rockall; Part IV. What Questions Are Being Asked by Current Clinical Trials?:: 15. Current clinical trials in ovarian cancer Christina Fotopoulou, Angus McIndoe, Jalid Sehouli and Hani Gabra; 16. Clinical trials in cervical cancer Karen Tipples and Melanie Powell; 17. Clinical trials in vulval cancer Tito Lopes; Part V. Consensus Views:: 18. Consensus views arising from the 60th Study Group:: Gynaecological Cancers:: Biology and Therapeutics; Index.
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