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Osteogenesis Imperfecta: From Diagnosis to Treatment

Osteogenesis Imperfecta: From Diagnosis to Treatment

9781685074999
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Description
Osteogenesis Imperfecta should be recognized as one of the most studied skeletal systemic dysplasias. Considering recent improvements of technology, the diagnostic and therapeutic strategies for this pathology might evolve in the future. This volume presents a collection of chapters covering a wide range of problems related to this condition. Three chapters of the book are dedicated to the modern and revised data on the molecular genetic aspects of the classification and pathogenesis of osteogenesis imperfecta. Detailed descriptions of somatic issues are presented for all body systems. Principles and results of bisphosphonate therapy and other methods of medical management are described by leading Russian specialists in this field. The most significant experience in Russia of medical treatment and physical therapy will arouse the interest of readers. The surgical part of the book is presented not only with a description of principles, methods and results of surgical interventions on the limbs, but also on the axial skeleton. Furthermore, two chapters are dedicated to the anaesthetic aspects of orthopaedic surgery in children with osteogenesis imperfecta. The substantiation is given to the methods of combined anaesthesia and pain management during the surgery, as well as in the immediate postoperative period, taking into account comorbidities. Telescopic rodding of long bones is a recognized gold standard in children with the disease, but there are multiple disadvantages of this approach. In the book we report new methods, combined techniques and technical tricks allowing to overcome inconveniencies and flaws of common steel telescopic intramedullary rods. At the end of the book, we discuss outcomes of complex management and the issue of patients quality of life after treatment performed by a multidisciplinary team. The high level of quality of life of patients is the prime and principle goal of our team. The data presented in this book are based, on one hand, on the personal, practical, and scientific experience of each author, and on the other hand, the entire team of authors works in collaboration with each other, coordinating their decisions and interventions with colleagues, thus ensuring continuity in treatment of children and adults suffering from Osteogenesis Imperfecta.
Product Details
92684
9781685074999
9781685074999

Data sheet

Publication date
2022
Issue number
1
Cover
hard cover
Pages count
273
Dimensions (mm)
155.00 x 230.00
Weight (g)
535
  • Foreword; Acknowledgements; Introduction; Definition, Pathogenesis, and Genetic Classification of Osteogenesis Imperfecta; Clinical Classification of Osteogenesis Imperfecta. Somatic Issues in Osteogenesis Imperfecta Children. Medical Treatment for Children with Osteogenesis Imperfecta; The Current State of Molecular Genetic Diagnostics in Various Forms of Osteogenesis Imperfecta; Physical Therapy Management in Osteogenesis Imperfecta; Orthotics and Assistive Devices for Osteogenesis Imperfecta; Anesthetic Management in Osteogenesis Imperfecta; Management of Pain in Patients with Osteogenesis Imperfecta During Operations on the Lower Limb; Osteogenesis Imperfecta: The Role and Place of Orthopedic Surgery of the Lower Extremities; Sliding Transphyseal Flexible Intramedullary Nailing in Children with Osteogenesis Imperfecta; Surgical Correction of Limb Deformities in Children with Osteogenesis Imperfecta: Experience of Turner Center; Use of Titanium Telescopic Rods in Osteogenesis Imperfecta Patients. Combined Technique and 3D Gait Analysis in OI Children; Spinal Pathology in Children and Adults with Osteogenesis Imperfecta; Surgical Correction of Spinal Pathology in Patients with Osteogenesis Imperfecta; Quality of Life and Outcomes of Reconstructive Surgery in Children with Osteogenesis Imperfecta; Conclusion.
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