Controlled drug delivery technology bridges the advances in medicine and genomics to the development of effective and innovative therapeutic products. This volume will examine recent research in this field and present the key findings. Advances in Controlled Drug Delivery will focus on the drug delivery of large molecules such as DNA and protein drugs. Novel technologies presented in the volume will include:: application of electroporation to deliver naked DNA, novel oraldelivery technologies, pulmonary delivery of protein drugs, delivery in the buccal mucosa, and novel approaches in target delivery to the brain using peptide vectors. In addition, the book will discuss the development of novel materials and sensors to enable the delivery of large molecules.
Preface; Naked DNA-Mediated Gene Therapy:: Clinical Application of Tissue Inhibitors of Matrix Metalloproteinase; Heparin and Gene Microarrays as a New Pharmacodynamic Tool; Oral Herparin Prevents Neointimal Growth Following Vascular Injury:: Implications for Potential Clinical Use; Peptide Vector-Mediated Drug Delivery to the Brain; Systemic and Topical Lung Delivery Using the AER, System; Controlled Growth Factor Delivery for Tissue Engineering; Controlled Drug Delivery to Drug-Sensitive and Multidrug Resistant Cells:: Effects of Pluronic Micelles and Ultrasound; Preparation of Novel Delivery of Macromolecular Drugs Using Boric Acid Mediated Amidation of Carboxylic Acids and Amenes; Loosely Cross-Linked Silicone Elastomer Blends and Topical Delivery; Hydrogels by Stereocomplex Formation and their Use As Drug DeliveryMatricies; Indexes; Author Indexes; Subject Indexes;
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