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Medical Genetics for the Modern Clinician

Medical Genetics for the Modern Clinician

9780781757607
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Description

Medical Genetics for the Modern Clinician is a concise, clinically oriented introductory genetics text for medical and allied health students, residents, and clinicians. The book focuses sharply on concepts that are most applicable to clinical practice.

Ethics sections in each chapter discuss ethical issues facing todays practitioner, such as counseling, risk assessment, and testing. More than 120 illustrations help students visualize concepts. Each chapter ends with USMLE-style review questions.

Appendices include a glossary and a Table of Genes that lists all genes covered in the text by chapter. Faculty resources, case studies, and downloadable full-color images will be available on connection.LWW.com/go/westman.

Product Details
Lippincott Williams & Wilkins
38838
9780781757607
9780781757607

Data sheet

Publication date
2005
Issue number
1
Cover
paperback
Pages count
256
Dimensions (mm)
178 x 254
Weight (g)
367

  • CHAPTER 1:: GENETICS IN THE PRACTICE OF MEDICINE

  • From Genetics to Genomics
  • Genetics and Preventive Medicine
  • Ethical Issues in Medical Genetics
  • USMLE-Style Questions

    CHAPTER 2:: DNA STRUCTURE, FUNCTION, AND REPLICATION:: A REVIEW

  • Basic Structure of DNA
  • Tertiary Structure of DNA
  • Mitochondrial DNA
  • Cell Cycle
  • Meiosis
  • USMLE-Style Questions

    CHAPTER 3:: CYTOGENETICS:: MICROSCOPIC GENETICS

  • Chromosome Morphology, Nomenclature, and Karyotyping
  • Techniques in Molecular Cytogenetics
  • Numerical Chromosomal Abnormalities
  • Structural Abnormalities
  • Mosaicism
  • Prenatal Clinical Techniques in Cytogenetics
  • USMLE-Style Questions

    CHAPTER 4:: MOLECULAR GENETICS:: GENE STRUCTURE, ORGANIZATION, AND CONTROL

  • Gene Structure
  • From Gene to Product
  • Genome Organization
  • Epigenetics
  • Clinically Relevant Laboratory Techniques
  • USMLE-Style Questions

    CHAPTER 5:: Changes and Repair at the Molecular DNA Level

  • Mutations
  • DNA Repair Mechanisms
  • SMLE-Style Questions

    CHAPTER 6:: MENDELIAN INHERITANCE:: OBSERVATION OF PHENOTYPES

  • Pedigree Construction
  • Inheritance Patterns
  • Genetic Counseling
  • Risk Assessment Based on Pedigree Analysis
  • Hardy-Weinberg Equilibrium
  • Prenatal Diagnosis of Mendelian Disorders
  • USMLE-Style Questions

    CHAPTER 7:: UNEXPECTED PHENOTYPES IN MENDELIAN DISORDERS:: MOLECULAR EXPLANATIONS

  • Variations in Dominant Phenotypes
  • Variations in Recessive Phenotypes
  • Variations in X-linked Phenotypes
  • Mitochondrial Inheritance
  • False Paternity
  • USMLE-Style Questions

    CHAPTER 8:: CANCER GENETICS

  • Genes and Cancer
  • Multistep Evolution in Cancer
  • Cancer Risk Assessment Counseling
  • Oncogenes
  • Tumor Suppressor Genes
  • USMLE-Style Questions

    CHAPTER 9:: COMPLEX DISEASES

  • Threshold Model
  • Modifier Genes
  • Tools for Study of Complex Diseases
  • Congenital Complex Diseases
  • Adult-Onset Complex Diseases
  • USMLE-Style Questions

    CHAPTER 10:: DEVELOPMENTAL GENETICS

  • Dysmorphology
  • Embryologic Development and Control Mechanisms
  • USMLE-Style Questions

    CHAPTER 11:: INDIVIDUALIZED MEDICINE

  • Pharmacogenomics
  • Individualized Drug Therapies
  • Disease Susceptibility
  • USMLE-Style Questions

    CHAPTER 12:: GENE THERAPY

  • Viral Vectors
  • Nonviral Vectors
  • USMLE-Style Questions

    Appendix:: Answers to USMLE-Style Questions

    Appendix:: Glossary

    Appendix:: Table of Genes Referenced

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