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Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, Second Edition

Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, Second Edition

9780071590341
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Description

The #1 guide to the principles and clinical applications of evidence-based medicine has just gotten better!

A Doodys Core Title ESSENTIAL PURCHASE for 2011!

No other resource helps you to put key evidence-based medicine protocols into daily clinical practice better than Users Guides to the Medical Literature.

An instant classic in its first edition, this detailed, yet highly readable reference demystifies the statistical, analytical, and clinical principles of evidence-based medicine, giving you a hands-on, practical resource that no other text can match.

Here, youll learn how to distinguish solid medical evidence from poor medical evidence, devise the best search strategies for each clinical question, critically appraise the medical literature, and optimally tailor evidence-based medicine for each patient. The new second edition of this landmark resource is now completely revised and refreshed throughout, with expanded coverage of both basic and advanced issues in using evidence-based medicine in clinical practice.

FEATURES::

  • Completely revised and updated to reflect the enormous expansion in medical research and evidence-based resources since the first edition
  • Innovative organization guides you from the fundamentals of using the medical literature to the more advanced strategies and skills for use in every day patient care situations
  • Abundant and current real-world examples drawn from the medical literature are woven throughout, and include important related principles and pitfalls in using medical literature in patient care decisions
  • Practical focus on the key issues in evidence-based practice:: What are the results? Are the results valid? How to I apply to results to the care of my patients?
  • More than 60 internationally recognized editors and contributors from the U.S., Canada, South America, Europe, and Asia -- the best of the best in the discipline
  • NEW coverage on how to::
    --Avoid being misled by biased presentations of research findings
    --Interpret the significance of clinical trials that are discontinued early
    --Influence clinician behavior to improve patient care
    --Apply key strategies for teaching evidence-based medicine
Also look for JAMAevidence.com, a new interactive database for the best practice of evidence based medicine.
Product Details
McGraw Hill / Medical
45768
9780071590341
9780071590341

Data sheet

Publication date
2008
Issue number
2
Cover
paperback
Pages count
860
Dimensions (mm)
152 x 229
Weight (g)
1012
  • Foreword
    Preface
    Part A. The Foundations
    1.How to Use the Medical Literature—and This Book—to Improve Your Patient Care
    2.The Philosophy of Evidence-Based Medicine
    3.What Is the Question?
    4.Finding the Evidence
    5.Why Study Results Mislead:: Bias and Random Error
    Part B. Therapy
    6.Therapy (Randomized Trials)
    7.Does Treatment Lower Risk? Understanding the Results
    8. Confidence Intervals
    9. Advanced Topics in the Validity of Therapy Trials
      9.1 An Illustration of Bias and Random Error
      9.2 Surprising Results of Randomized Trials
      9.3 Randomized Trials Stopped Early for Benefit
      9.4 The Principle of Intention to Treat
      9.5 N-of-1 Randomized Controlled Trials
      9.6 Clinical Decision Support Systems
    10. Advanced Topics in the Results of Therapy Trials
      10.1 Hypothesis Testing
      10.2 Understanding the Results:: More About Odds Ratios
      10.3 What Determines the Width of the Confidence Interval?
      10.4 Composite endpoints
      10.5 Measuring Patients Experience
    11. Advanced Topics in Applying the Results of Therapy Trials
      11.1 Applying Results to Individual Patients
      11.2 Example Numbers Needed to Treat
      11.3 Dealing with Misleading Presentations of Clinical Trial Results
      11.4 Surrogate Outcomes
      11.5 Qualitative Research
    Part C. Harm (Observational Studies)
    12. Harm (Observational Studies)
    13. Advanced Topics in Harm:: Correlation and Regression
    Part D. Diagnosis
    14.The Process of Diagnosis
    15. Differential Diagnosis
    16. Diagnostic Tests
    17.Advanced Topics in Diagnosis
      17.1 Spectrum Bias
      17.2 Examples of Likelihood Ratios
      17.3 Measuring Agreement Beyond Chance
      17.4 Clinical Prediction Rules
    Part E. Prognosis
    18.Prognosis
    Part F. Summarizing the Evidence
    19.Summarizing the Evidence
    20. Advanced Topics in Systematic Reviews
      20.1 Reporting Bias
      20.2 Fixed-Effects and Random-Effects Models
      20.3 Making Sense of Variability in Study Results
      20.4 When to Believe a Subgroup Analysis
    Part G. Moving From Evidence to Action
    21.How to Use a Patient Management Recommendation
    22.Advanced Topics in Moving from Evidence to Action
      22.1 Economic Analysis
      22.2 Decision Making and the Patient
      22.3 Moving From Evidence to Action:: Recommendations About Screening
      22.4 Grading Recommendations
      22.5 Drug Class Effects
      22.6 Parallel but Separate Goals:: Evidence-Based Practitioners and Evidence-Based Care
      22.7 Changing Behavior to Apply Best Evidence in Practice
      22.8 Teachers Guides to the Users Guides
    Glossary
    Index
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