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Hepatic Insulin Resistance & Nonalcoholic Fatty Liver Disease

Hepatic Insulin Resistance & Nonalcoholic Fatty Liver Disease

9781612095288
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Description
Insulin resistance (IR) and metabolic syndrome are associated with the pathogenesis and progression of non-alcoholic fatty liver disease (NAFLD). It encompasses a spectrum of hepatic pathology, ranging from simple steatosis in its most benign form (fatty liver), going through nonalcoholic steatohepatitis (NASH) in its intermediate form, until cirrhosis and hepatocellular carcinoma, its most advanced forms. This book presents current research on the background of fatty acid oxidation; hepatic steatosis and its progression to NASH and cirrhosis; fibrosis and myofibroblastic cells differentiation; methods of diagnosis; clinical features and laboratory tests and, finally, rodent NAFLD and NASH models.
Product Details
73198
9781612095288
9781612095288

Data sheet

Publication date
2011
Issue number
1
Cover
paperback
Pages count
85
Dimensions (mm)
230.00 x 155.00
Weight (g)
166
  • Introduction; Triglyceride Storage Regulation in Hepatocytes; Impairment of Fatty Acid Oxidation; NAFLD & Its Progression to NASH & Cirrhosis; Steatosis; Inflammation; Fibrosis & Myofibroblastic Cell Differentiation; Methods of Diagnosis; Rodent NAFLD & NASH Models; Conclusions; Index.
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