Proteomics is a mature research tool in the life sciences, and it can be a powerful addition to the forensic science toolbox. This work presents several areas in which proteomics was used to answer forensic questions. Illustrating current applications of proteomic methods, this work introduces opportunities for proteomics to answer compelling questions in forensic science and biosecurity. These case studies will be valuable to both practicing forensic scientists and researchersdeveloping proteomics methods.
Chapter 1. Introduction to Forensic Proteomics, Eric D. Merkley; Chapter 2. A Proteomics Tutorial, Eric D. Merkley, Brooke L. D. Kaiser, and Helen Kreuzer; Chapter 3. Proteomic Sample Preparation Techniques: Toward Forensic Proteomic Applications, Carrie Nicora, Marina Gritsenko, Anna Lipton, Karen L. Wahl, and Kristin E. Burnum-Johnson; Chapter 4. NextGen Serology: Leveraging Mass Spectrometry for Protein-Based Human Body Fluid Identification, Heather E. McKiernan, Catherine O. Brown, Luciano Chaves Arantes, Phillip B. Danielson, and Kevin M. Legg; Chapter 5. Informatics Approaches to Forensic Body Fluid Identification by Proteomic Mass Spectrometry, Wenke Liu, Erin Butler, Heyi Yang, David Fenyo, and Donald Siegel; Chapter 6. Fingermarks as a New Proteomic Specimen: State of the Art and Perspective of In Situ Proteomics, Simona Francese and Cristina Russo; Chapter 7. Human Identification Using Genetically Variant Peptides in Biological Forensic Evidence, Fanny Chu, Katelyn E. Mason, Deon S. Anex, Phillip H. Paul, and Bradley R. Hart; Chapter 8. Proteomics in the Analysis of Forensic, Archaeological, and Paleontological Bone, Michael Buckley; Chapter 9. Proteomics for Microbial Forensics, Eric D. Merkley; Chapter 10. ISO 17025 Accreditation of Method-Based Mass Spectrometry for Bioforensic Analyses, Stephen R. Cendrowski and Alaine M. Garrett; Chapter 11. Unambiguous Identification of Ricin and Abrin with Advanced Mass Spectrometric, Assays Suzanne R. Kalb and Francois Becher; Chapter 12. Challenges in the Development of Reference Materials for Protein Toxins, R. Zeleny, A. Rummel, D. Jansson, and B. G. Dorner; Chapter 13. The Statistical Defensibility of Forensic Proteomics, Kristin H. Jarman and Eric D. Merkley; Editors Biographies; Author Index; Subject Index;
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