In this issue of Otolaryngologic Clinics, guest editors Drs. Amy Y. Chen and Michael C. Singer bring their considerable expertise to the topic of Thyroid and Parathyroid Disease. Top experts in the field discuss key topics such as avoiding complications of thyroidectomy:: preservation of parathyroid glands; RLN monitoring; RFA for benign nodules and for cancer, too; surgery for secondary hyperparathyroidism; autofluorescence of parathyroid glands; and more.