Type 2 diabetes is a major health problem reaching epidemic dimensions. Its complications, micro- and macrovascular, have a great impact in health economics as well as in the diabetic patients quality of life. In this book, the authors present current research in the study of the causes, treatment and preventive strategies of type 2 diabetes. Topics include the molecular genetics of type 2 diabetes mellitus; the pharmacogenetics and personalised therapy of oral antidiabetic drugs; gastric bypass and sleeve gastrectomy as effective treatment strategies in obese patients with type 2 diabetes; ACP1 genetic variability; and the study of biomarkers for diabetes mellitus type 2 and the role of high dose thiamine.
Preface; An Overview & Molecular Genetics of Type 2 Diabetes Mellitus; Type 2 Diabetes:: Causes, Treatment & Preventive Strategies; Pharmacogenetics & Personalized Therapy of Oral Antidiabetic Drugs; Roux-en-Y Gastric Bypass & Sleeve Gastrectomy are Effective Treatment Strategies in Obese Individuals with Type 2 Diabetes Mellitus; ACP1 Genetic Variability & the Development of Diabetes in Obese Subjects; Treatment of Type 2 Diabetes:: Adjustments to Changes in Insulin Resistance & Secretion & to Variations in Basal & Prandial Glucose along the Diabetes Continuum; Study of Protein Biomarkers for Diabetes Mellitus Type 2 & Role of High Dose Thiamine on their Level; Index.
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