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Pathological Basis of Oral and Maxillofacial Diseases

Pathological Basis of Oral and Maxillofacial Diseases

9781119989202
629.94 zł
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2025-01-17

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Description

A comprehensive guide for integrating pathology into a clinical setting.

Pathological Basis of Oral and Maxillofacial Diseases presents the basic principles involved in disease mechanisms in an easy-to-understand way. By integrating recent advances in molecular, immunologic, and genetic understanding of oral disease, the book helps readers enhance their knowledge and its application in a clinical setting.

This book is divided into nine sections, covering key topics such as inflammation, genetic diseases, and neoplasia, with contributions from over 50 international authors. Diagrams, clinical, radiographic, and histopathology images and tables supplement the text, and the editors have ensured a consistent approach throughout.

Topics covered in Pathological Basis of Oral and Maxillofacial Diseases include::

  • The influences of nutrition and the environment
  • Cellular structure and function, causes and mechanisms of cellular pathology.
  • Immunity and host defence mechanisms, immune dysfunctions affecting the oro-facial complex.
  • Inflammation and inflammatory diseases of the oro-facial complex
  • Human microbiome, with reference to dysbiosis in dental caries and periodontal diseases
  • Oral manifestations of systemic diseases and the oral-systemic link and its impact on general and oral health
  • Oral potentially malignant and malignant disorders that are a major threat to global public health.

Bridging the gap in dental training programs from basic medical science in the initial years to clinical practice, Pathological Basis of Oral and Maxillofacial Diseases is an essential reference for dental students, trainees and practitioners seeking to grasp the pathological basis of disease and apply that knowledge to the oral and maxillofacial regions.

Product Details
Wiley-Blackwell
103018
9781119989202

Data sheet

Publication date
2025
Issue number
1
Cover
paperback
Pages count
688

  • About the Editors xi

    List of Contributors xiii

    Foreword xviii

    Preface xix

    Section 1 Pathology as the Foundation of Medicine 1

    1 Introduction to Pathology 3
    S. R. Prabhu and Suja Pillai

    2 Global Scenario, Aetiology and Risk Factors Associated with Oral and Maxillofacial Diseases: An Overview 11
    Nesa Aurlene Jayadhas and Santosh Kumar Tadakamadla

    3 The Role of Laboratory Diagnosis in Oral and Maxillofacial Pathology: An Overview 27
    Hannah Walsh and Daniel J. Brierley

    Section 2 Homeostasis and Cellular Pathology 39

    4 Homeostasis and Influences of Environment and Nutrition 41
    A. V. Chalapathi Rao and S. R. Prabhu

    5 Cellular Structure and Function 51
    Suheyla Kaya Copyrighted Material

    6 Cell Injury: Causes, Mechanisms and Responses 64
    S. R. Prabhu

    7 The Structure and Function of the Oral Mucosa 82
    Gargi Sarode and Sachin Sarode

    8 Cellular Mechanisms of Ageing of Oral Tissues 99
    Jeremy Lau, Agnieszka Frydrych and Omar Kujan

    9 Endocrine and Metabolic Dysfunction and Oro- Facial Diseases 108
    Prazwala Chirravur and Pradeep Chirravur

    Section 3 Defence Mechanisms Against Disease 133

    10 Immunity and Host Defence Mechanisms in Oral Health and Disease 135
    Irene Lafuente-Ibánez de Mendoza and José M. Aguirre-Urizar

    11 Immune Dysfunctions Affecting the Oro-Facial Complex 147
    Yeshwant Rawal

    12 Pathology of Inflammation and Inflammatory Diseases of the Oro- Facial Complex: An Overview 175
    S. R. Prabhu

    13 Cellular and Molecular Mechanisms of Healing of Cutaneous and Oral Mucosal Wounds 196
    H. Ibrahim Korkmaz and Susan Gibbs

    14 Healing of the Dental Pulp and Periodontal Tissues, Extraction Socket and BoneFracture 204
    Sachin Sarode and Gargi Sarode

    Section 4 Clinical Genetics and Developmental Pathology 227

    15 The Human Genome and Inheritance: Key Concepts 229
    Yucel Erbilgin and Muge Sayitoglu

    16 Heritable Diseases with Examples Involving the Oro- Facial Complex 245
    Fadi Titinchi and Johan Opperman

    17 Non- heritable Developmental Disorders with Examples Involving the Oral- Maxillofacial Complex 274
    John Anthony Ozolek

    Section 5 Infectious and Systemic Diseases 293

    18 Human Microbiome in Health and Disease with Reference to Dysbiosis in Dental Caries and Periodontal Diseases 295
    Preethi Balan, Nadeeka Udawatte and Chaminda Jayampath Seneviratne

    19 Pathology of Infection and Infectious Diseases of the Oro-Facial Complex 310
    Nagamani Narayana and John Casey

    20 Oral-systemic Link and Its Impact on General and Oral Health 339
    Dáire Shanahan and Sarah Jane George

    21 Orofacial Manifestations of Systemic Diseases: An Overview 362
    Philip Atkin

    22 Adverse Drug Reactions in the Orofacial Complex 377
    Sue-Ching Yeoh

    Section 6 Disorders of Cell and Tissue Growth 407

    23 Neoplasia: Basic Concepts 409
    Omar Kujan and Philip Sloan

    24 Molecular Basis of Cancer 415
    Lalima Tiwari and Omar Kujan

    25 Host Defences Against Cancer 429
    Andreia Bufalino

    26 WHO Classification of Tumours: An Overview 440
    Muhammed Yakin and Richard Logan

    27 Dysplasia, Precancer and Oral Potentially Malignant Disorders 449
    Agnieszka Frydrych and Omar Kujan

    Section 7 Neoplastic Diseases of the Oral Mucosa and Salivary Glands 475

    28 Global Burden, Risk factors and Pathobiology of Malignant Neoplasms of the Oral Mucosa and the Oropharynx 477
    Paul Hankinson and Syed Ali Khurram

    29 Presentation, Diagnosis and Prognosis of Squamous Cell Carcinomas of the Oral Mucosa and Oropharynx 498
    Selvam Thavaraj and Adam Jones

    30 Global Burden, Classification, Pathobiology, Genetics and Prognosis of Salivary Gland Neoplasms 531
    Lucas Lacerda de Souza, Marcio Ajudarte Lopes, Pablo Agustin Vargas and Syed Ali Khurram

    Section 8 Diseases of the Oral and Maxillofacial Skeleton 567

    31 Classification and Pathogenesis of Odontogenic and Non- odontogenic Jaw Cysts 569
    Paul M. Speight and Merva Soluk Tekkesin

    32 Global Burden, Pathobiology, Genetics and Behaviour of Odontogenic Neoplasms 585
    Keith Hunter and Merva Soluk Tekkesin

    33 Pathogenesis and Behaviour of Fibro- osseous and Giant- Cell Lesions of the Jaw Bones 604
    Lisette Collins and Merva Soluk Tekkesin

    Section 9 Pain Disorders 615

    34 Pathophysiology of Orofacial Pain 617
    Janani Ravichandran, Guru O., Ramesh Balasubramaniam and Barry Sessle

    35 Genetics, Lifestyle and Psychosocial Considerations in Orofacial Pain 639
    Lasanthini Weerakkody, Jeremy Lau, Kavitha Vegunta, Davis C. Thomas and Ramesh Balasubramaniam

    Index 658

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