Two of the most widely used terms in medicine are placebo and placebo effect, even though it is not always clear what exactly they mean. Recent progress in biomedical research has allowed a better clarification of the placebo effect. We now know that this is an active psychobiological phenomenon which takes place in the patients brain and that is capable of influencing both the course of a disease and the response to a therapy. Placebo Effects (3e) is a significantly updated and expanded new edition of a highly successful and critically acclaimed textbook on placebos. It is the first book to emphasize that there are many placebo effects and reviews them critically in different medical conditions, such as neurological and psychiatric disorders, cardiovascular and respiratory diseases, immune and hormonal responses, as well as oncology, surgery, sports medicine and acupuncture. In addition, it looks at the psychosocialcontext, which is considered crucial to the placebo effect. For example what the doctor says to the patient, as well as their attitude, can greatly influence the placebo effect. Exhaustive in its coverage, and written by a world authority in the field, this is the definitive reference textbook on the placebo effect - one that is essential for researchers and clinicians across a wide range of medical specialities.
The patients brain: setting the stage for understanding placebo effects; A brief evolutionary account of medical care; Emergence and development of scientific medicine; Feeling sick: A combination of bottom-up and top-down events; Seeking relief: The activation of motivational and reward circuits; Meeting the therapist: A look into trust, hope, empathy and compassion mechanisms; The brain of the demented patient; Placebo effects: General concepts and mechanisms; The traditional concept of placebo; A modern view of placebo and placebo-related effects; Placing placebo effects within the context of the doctor-patient relationship as a defence mechanism; Disease-based classification of placebo effects - Most studied conditions; Pain; Diseases of the nervous system; Mental and behavioural disorders; Immune and endocrine systems; Disease-based classification of placebo effects - Less studied conditions; Cardiovascular and respiratory system; Gastrointestinal and genitourinary disorders; Special medical conditions and therapeutic interventions; Clinical, ethical and methodological considerations; Clinical-ethical implications and applications; How to run a placebo study: A closer look into complex experimental designs; Beyond the healing context; Beyond the healing context; Everyday life;
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