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Critical Thinking in Clinical Research

Critical Thinking in Clinical Research

Applied Theory and Practice Using Case Studies

9780199324491
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Description
One of the most crucial skills a clinician, scientist, or student can learn is to create, conduct, and interpret the conclusions of a clinical study. Critical Thinking in Clinical Research teaches these fundamentals in four distinct sections, called units:: the first unit focuses on issues surrounding the design of a study such as population, question selection, randomization, and blinding; Unit 2 presents statistical methods such as analyzing data collected, how topresent and discuss the data concisely; the third unit covers practical aspects such as methodology, organizational considerations, principles of trial conduct and reporting; and the final unit delves into study designs, providing the advantages and drawbacks of each design style. Each chapter begins with a short introduction, followed by a hypothetical case that challenges the reader to make decisions, to consider pros and cons of specific approaches, and to evaluate options based on specific conditions. Knowing how to critically read and understand scientific papers and to collect, analyze, and interpret research data, which they in turn can then present in their own scientific manuscript makes this book the perfect resource for anyone looking to contribute to thewealth of scientific and medical inquiry.
Product Details
OUP USA
88049
9780199324491
9780199324491

Data sheet

Publication date
2018
Issue number
1
Cover
paperback
Pages count
536
Dimensions (mm)
156 x 235
Weight (g)
862
  • Section 1; CHAPTER 1: Basics of Clinical Research: Introduction to Clinical Research; Rui Nakamura, Faiza Khawaja, Laura Castillo, Felipe Fregni, Steven Freedman; CHAPTER 2: Selection of the Research Question; Keiko Ueda and Lotfi B. Merabet; CHAPTER 3: Study Population; Sandra Carvalho and Felipe Fregni; CHAPTER 4: Basic Study Designs; Alexandra Gomez, Felipe Fregni, and Vera Novak; CHAPTER 5: Randomization; Juliana C Ferreira, Ben Illigens, and Felipe Fregni; CHAPTER 6: Blinding; Rita Tomas and Joseph Massaro; CHAPTER 7: Recruitment and Adherence; Timo Siepmann, Ana Isabel Penzlin, and Felipe Fregni; Section 2; CHAPTER 8: Basics of Statistics; Claudia Kimie Suemoto and Catherine Lee; CHAPTER 9: Parametric Statistical Tests; Ben Illigens, Fernanda Lopes, and Felipe Fregni; CHAPTER 10: Non-parametric Statistical Tests; Felipe Fregni and Fernanda Lopes; CHAPTER 11: Sample Size Calculation; Mohammad Azfar Qureshi and Jessica Paulus; CHAPTER 12: Survival Analysis; Jorge Leite and Sandra Carvalho; CHAPTER 13: Other Issues in Statistics I (missing data, intention-to-treat analysis and covariate adjustment); Tamara Jorquiera and Hang Lee; CHAPTER 14: Other Issues in Statistics II (Subgroup analysis and meta-analysis); Jorge Leite and Munir Boodhwani; Section 3; CHAPTER 15: Non-Inferiority Design; Raquel Ajub Moyses, Valeriam Angelim, and Scott Evans; CHAPTER 16: Observational Studies; Minou Djannatian and Clarissa Valim; CHAPTER 17: Confounders And Using The Method Of Propensity Scores; Chin Lin; CHAPTER 18: Adaptive Trials and Interim Analysis; Priscila Andrade, Nazem Atassi, and Laura Castillo-Saavedra; Section 4; CHAPTER 19: Integrity in Research: Authorship & Ethics; Sandra Carvalho and Gustavo Rivara; CHAPTER 20: The Business of Clinical Research; Livia Caroline, Mariano Compte, and Jorge Leite; CHAPTER 21: Design and Analysis of Surveys; Ana R. Martinez and Ines C.R. Henriques; CHAPTER 22: Assessing Risk and Adverse Events; Laura Castillo-Saavedra, Suely Matsubayashi, Faiza Khawaja, John Ferguson, and Felipe Fregni; CHAPTER 23: Manuscript Submission; Alma Tamara Sanchez Jimenez and Felipe Fregni;
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