In this issue of Medical Clinics of North America, guest editors Drs. Alexander Fanaroff and John W. Hirschfeld, Jr., bring their considerable expertise to the topic of Patient Management with Stable Ischemic Heart Disease. Top experts provide insights into newer diagnostic modalities for patients presenting with symptoms of stable ischemic heart disease, review the pillars of medical management as well as emerging cardiometabolic therapies, provide updates on the role of revascularization, and reveal gender, racial, ethnic, and socioeconomic disparities in the presentation and management of stable ischemic heart disease.