In this issue of Heart Failure Clinics, guest editors Drs. Vijay Rao and Geetha Bhatt bring their considerable expertise to the topic of Novel Non-pharmacological Approaches to Heart Failure. Recent years have seen a multitude of new devices and non-pharmacologic approaches to heart failure (HF), which, in the properly selected patient, can have significant impacts on morbidity and mortality. This issue provides a contemporary summary of these innovative approaches from leaders in the field.