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Drug-Induced Valvular Heart Disease

Drug-Induced Valvular Heart Disease

9781616689780
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Description
The notion that drugs can induce valvular heart disease (VHD) has occurred since the sixties and has received a lot of attention in recent years. Overstimulation of the serotonin 2B receptor (5-HT2B) leads to valvular fibroblast proliferation and thickening of the valvular leaflets with reduced mobility and regurgitation as a consequence. This book focuses on different aspects of this distinct kind of valvulopathy including pathophysiology of drug-induced VHD, histopathological and echocardiographic characteristics,drugs associated with VHD, the influence of cumulative drug dose and risk factors and others.
Product Details
73488
9781616689780
9781616689780

Data sheet

Publication date
2011
Issue number
1
Cover
paperback
Pages count
52
Dimensions (mm)
215.00 x 140.00
Weight (g)
98
  • Introduction; Pathophysiology of Drug-Induced Valvular Heart Disease; Morphological & Echocardiographic Characteristics; Drugs Associated with Valvular Heart Disease; Influence of Drug Dose, Treatment Duration & Risk Factors; Natural Course of Toxic Valvulopathy; Small Animal Models of Drug-Induced Valvular Heart Disease; Practical Recommendations for the Use of Potential Valvulopathic Drugs; Index.
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