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Drug-Induced Valvular Heart Disease
9781616689780
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Description
The notion that drugs can induce valvular heart disease (VHD) has occurred since the sixties and has received a lot of attention in recent years. Overstimulation of the serotonin 2B receptor (5-HT2B) leads to valvular fibroblast proliferation and thickening of the valvular leaflets with reduced mobility and regurgitation as a consequence. This book focuses on different aspects of this distinct kind of valvulopathy including pathophysiology of drug-induced VHD, histopathological and echocardiographic characteristics,drugs associated with VHD, the influence of cumulative drug dose and risk factors and others.
Product Details
73488
9781616689780
9781616689780
Data sheet
- Publication date
- 2011
- Issue number
- 1
- Cover
- paperback
- Pages count
- 52
- Dimensions (mm)
- 215.00 x 140.00
- Weight (g)
- 98
- Introduction; Pathophysiology of Drug-Induced Valvular Heart Disease; Morphological & Echocardiographic Characteristics; Drugs Associated with Valvular Heart Disease; Influence of Drug Dose, Treatment Duration & Risk Factors; Natural Course of Toxic Valvulopathy; Small Animal Models of Drug-Induced Valvular Heart Disease; Practical Recommendations for the Use of Potential Valvulopathic Drugs; Index.
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