Diabetes and Cardiovascular Disease

Integrating Science and Clinical Medicine

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Brand: LWW

ISBN: 9780781740531

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Description

This text thoroughly reviews the latest findings and concepts on the vascular biology of diabetes mellitus, the clinical vascular manifestations of diabetes, and the therapeutic options available for diabetic patients with vascular disease. The first section provides an in-depth understanding of fundamental principles and recent discoveries regarding diabetes mellitus and vascular biology. The second, clinically oriented section includes chapters on the economic implications of diabetes mellitus, risk profiling patients with diabetes, optimizing adjunctive therapies, and treatment strategies for diabetic patients with coronary and peripheral artery disease. Summaries of important clinical trials are included to provide an evidence-based approach to treatment.

Product Details

Brand LWW

Reference 42510

EAN13 9780781740531

ISBN 9780781740531

Data sheet

Publication date: 2003
Issue number: 1
Cover: hard cover
Pages count: 480
Dimensions (mm): 4516 x 6452
Weight (g): 512287

Part I Vascular Biology
Structure and Function of the Vessel Wall, 3
Mario B. Marrero and David M. Stern
Antioxidants, Oxidative Stress, and Inflammation in Diabetes, 19
Sridevi Devaraj, Sonia Vega-López, and Ishwarlal Jialal
Role of Protein Kinase C Isoforms in Diabetic Vascular Dysfunction, 37
Zhiheng He, Ronald C.W. Ma, and George L. King
Aldose Reductase and Vascular Stress, 55
Ravichandran Ramasamy and Peter J Oates
Peroxisome Proliferator-Activated Receptors and Diabetic Vasculature, 75
Peter J. Little, Duncan J. Topliss, Sunder Mudalier, and Ronald E. Law
Receptor-Dependent Vascular Stress in Diabetes, 93
Ann Marie Schmidt, Barry I. Hudson, Shi-Fang Yan, and David M. Stern
Genetic Determinants of Late Diabetic Complications, 111
Alessandro Doria, James H. Warram, and Andrzej S. Krolewski
Diabetic Retinopathy and Vascular Endothelial Growth Factor, 133
Hans-Peter Hammes and Georg Breier

Part II Clinical Topics

Epidemiology of Diabetes Mellitus and Cardiovascular Disease, 153
Sunil V. Rao and Darren K. McGuireEconomic Implications of Diabetes Mellitus, 179
John D. Nachtigal and Cathryn A. CarrollObesity, 199
Mark W. Conard and Walker S. Carlos PostonDiabetes Treatment, 219
William L. IsleyEndothelial Dysfunction, 239
Joshua A. BeckmanPlatelet Dysfunction, 251
Robert Kelly and Steven R. SteinhublDiabetes, Impaired Fibrinolysis, and Thrombosis, 269
Peter J. Grant and Lucinda K.M. SummersRestenosis, 293
David S. Lee and Marc S. PennThe Renin-Angiotensin System, Nephropathy, and Hypertension, 315
Roberto Trevisan and Giancarlo VibertiLipoprotein Abnormalities, 337
William L. Isley and William S. HarrisDiabetes Mellitus and Ischemic Heart Disease, 355
Benjamin H. Trichon and Matthew T. RoeDiabetes and Coronary Revascularization, 379
Deepak P. Vivekananthan and Deepak L. BhattDiabetes and Peripheral Artery Disease, 403
Roberto A. Corpus
Appendix A. Adjunctive Pharmacology of Diabetes:: Chain of Evidence, 423
Maureen E. Knell, Jared T. Lurk, and Jennifer M. RothAppendix B. Synopsis of Major Cardiovascular Trials Involving Diabetic Patients, 469
Avinash KhannaSubject Index, 487