This issue of the Thoracic Surgery Clinics is devoted to Management of N2/IIIA Lung Cancer and will address the following topics:: Defining N2 disease; molecular detection and immunocytochemistry of N2 disease; radiographic staging of N2 disease; minimally invasive staging of N2 disease (EBUS/EUS, mediastinoscopy and VATS ); intraoperative staging and surgical management of N2 disease; definitive chemo/RT for N2 disease; neoadjuvant therapy for N2 disease; restaging after neoadjuvant therapy for N2 disease; adjuvant therapy for N2 disease; and management algorithms for N2 disease.