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Mechanistic Enzymology

Mechanistic Enzymology

Bridging Structure and Function

9780841298842
897.00 zł
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Description
Theoretical, computational, and experimental perspectivesMechanistic enzymology is the basis of many applications, from drug design to cleaning products. This work offers a timely synopsis of advanced understanding of enzymatic regulation and function. Chapters are authored by both those in traditional protein studies and those challenging paradigms, bridging disconnected fields, and presenting a unified view of enzyme mechanisms. Biochemists, structural biologists, and other researchers working with enzymes will find this work useful. Each chapteris written to maximize accessibility for students and bridge developed theory with current scientific literature. This volume serves as a valuable teaching tool to introduce foundational topics to students, bridging distantly connected fields toward the presentation of a unified view of enzymemechanism.
Product Details
OUP USA
93323
9780841298842
9780841298842

Data sheet

Publication date
2021
Issue number
1
Cover
hard cover
Pages count
224
Dimensions (mm)
178 x 254
Weight (g)
540
  • Chapter 1: Introduction: Viewing Science through Multiple Lenses, Justin M. Miller; Chapter 2: Enzyme Active Site Architecture: The Whole Is Greater Than the Sum of the Parts, Justin M. Miller and Chad Brambley; Chapter 3: Integrative Structural Biology: Using X-ray Crystallography, Small-Angle X-ray Scattering, and Cryogenic Electron Microscopy to Determine Protein Structures, Jamie R. Wallen; Chapter 4: Evolving Role of Conformational Dynamics in Understanding Fundamental Biomolecular Behavior, David Ban; Chapter 5: KatG Structure and Mechanism: Using Protein-Based Oxidation to Confront the Threats of Reactive Oxygen, Jessica R. Krewall, Laura E. Minton, and Douglas C. Goodwin; Chapter 6: Understanding Enzyme Catalysis Mechanism Using QM/MM Simulation Methods, Tao Yu and Hong Guo; Chapter 7: Tunneling through the Barriers: Resolving the Origins of the Activation of C-H Bonds Catalyzed by Enzymes, Chris Whittington, John Latham, and Adam R. Offenbacher; Chapter 8: Enzymatic Biodegradation by Exploring the Rational Protein Engineering of the Polyethylene Terephthalate Hydrolyzing Enzyme PETase from Ideonella sakaiensis 201-F6, Mitch H. Weiland; Editor Biography; Author Index; Subject Index;
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