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Glycan-based Cellular Communication

Glycan-based Cellular Communication

Techniques for Carbohydrate-Protein Interactions

9780841298989
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Description
Glycan interactions with a variety of glycan binding proteins (GBPs) play a significant role in cell-cell communication, immune evasion, and pathogenic processes. Understanding these interactions is critical to regulating cellular processes and has tremendous therapeutic significance. However, methods to study glycan interactions are relatively limited due to several structural and functional properties of glycans.This work explores specially adapted methods of study, with advances such as glycan microarrays, glycosylated conductive polymers, Luminex bead-based arrays, metabolic labelling, cell surface engineering, and chemo enzymatic labeling. This volume serves as a valuable tool for researchers and industry workers interested in developing and adapting technologies in the detection of glycan-GBP interactions.
Product Details
OUP USA
93309
9780841298989
9780841298989

Data sheet

Publication date
2021
Issue number
1
Cover
hard cover
Pages count
224
Dimensions (mm)
178 x 254
Weight (g)
708
  • Preface; Chapter 1. Recent Advancements in Arrayed Technologies and Emerging Themes in the Identification of Glycan-Protein Interactions, Eugene Joeh, Zak Vilen, Timothy OLeary, and Mia L. Huang; Chapter 2. Insights into Antibody-Carbohydrate Recognition from Neoglycoprotein Microarrays, Jeffrey C. Gildersleeve; Chapter 3. Generation of a Heparan Sulfate Mutant Cell Library and Its Application to Determine the Structure-Function Relationship of Heparan Sulfate in Facilitating FGF2-FGFR1 Signaling, John Faulkner, Xuehong Song, and Lianchun Wang; Chapter 4. Polyvalent Glycan-Quantum Dots as Multifunctional Structural Probes for Multivalent Lectin-Carbohydrate Interactions, James Hooper, Yuan Guo, and Dejian Zhou; Chapter 5. Automated Identification of Lectin Fine Specificities from Glycan-Array Data, Zachary Klamer and Brian Haab; Chapter 6. Label-Free Biosensors for Studying Carbohydrate-Protein Interaction, Abdul Rehman, Lei Li, and Xiangqun Zeng; Chapter 7. Sketching the Glycan Hallmark of Intact Cells Using Lectin Microarray, Sheng-Ce Tao and Shumin Zhou; Chapter 8. Methods to Investigate Innate Immune Receptors and Their Carbohydrate-Based Ligands, Siavash Mashayekh, Elizabeth A. DAmbrosio, and Catherine L. Grimes; Chapter 9. Morphogenesis of the Mammalian Tectorial Membrane:: Unveiling the Surface Roles of a Matrix Organizer, Alpha Tecto, Dong-Kyu Kim and Sungjin Park; Chapter 10. Mass Spectrometric Analysis of Protein Glycosylation, He Zhu, Arya Aloor, Cheng Ma, Shukkoor M. Kondengaden, and Peng George Wang; Editors Biographies; Author Index; Subject Index;
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