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Targeted Nanosystems for Therapeutic Applications

Targeted Nanosystems for Therapeutic Applications

New Concepts, Dynamic Properties, Efficiency, and Toxicity

9780841233836
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Description
Despite the potential of nanoparticles in nanomedicine and decades of research, it remains challenging to actively target nanoparticles. Focusing on recent research and development, this book identifies and presents potential new paradigms and ideas to meet practical demands in different biomedical areas. The book reveals new developments and identifies new clinically relevant targets and strategies to increase targeting efficiency and reduce toxicity. Scientists in chemical,biological, pharmaceutical, and clinical roles in academia and the broader industry will find this book interesting.
Product Details
OUP USA
88523
9780841233836
9780841233836

Data sheet

Publication date
2020
Issue number
1
Cover
hard cover
Pages count
368
Dimensions (mm)
152 x 227
Weight (g)
724
  • Preface ; Chapter 1. Targeted Therapeutic Genome Engineering: Opportunities and Bottlenecks in Medical Translation, Jessica A. Kretzmann, David C. Luther, Marck Norret, Vincent M. Rotello, and K. Swaminathan Iyer; Chapter 2. Aerosol Delivery to the Airways Using Cationic Lipid Nanocomplexes in a Perspective of Cystic Fibrosis Treatment, Mathieu Berchel, Paul-Alain Jaffr?s, Tony Le Gall, and Tristan Montier; Chapter 3. Hybrid Nucleic Acid Nanocapsules for Targeted, Enzyme-Specific Drug Delivery and Intracellular Gene Regulation, Joshua J. Santiana, Saketh Gudipati, Alyssa K. Hartmann, and Jessica L. Rouge; Chapter 4. A Novel Polysaccharide Carrier for Functional Oligonucleotides: Immunocyte Targeting through ß-Glucan Receptors, Noriko Miyamoto, Shinichi Mochizuki, and Kazuo Sakurai; Chapter 5. Thiourea-Functional Bioreducible Poly(amido amine)s in Gene Delivery, M. Rach?l Elzes, Guoying Si, Johan F. J. Engbersen, and Jos M. J. Paulusse; Chapter 6. Non-Crosslinking Aggregation of DNA-Functionalized Gold Nanoparticles for Gene Diagnosis and Directed Assembly, Guoqing Wang, Yoshitsugu Akiyama, Naoki Kanayama, Tohru Takarada, and Mizuo Maeda; Chapter 7. Self-Assembly of Noble Metal-Based Hybrid Nanostructures Using a Combination of Colloidal and Aerosol-Based Approaches, Hung-Li Wang and De-Hao Tsai; Chapter 8. Mechanisms of Actively Triggered Drug Delivery from Hard Nanoparticle Carriers, Ajmeeta Sangtani, Megan E. Muroski, and James B. Delehanty; Chapter 9. Inclusion Complexes in Drug Delivery and Drug Targeting: Formation, Characterization, and Biological Applications, Rajesh K. K. Sanku, Ozlem O. Karakus, Monica Ilies, and Marc A. Ilies; Chapter 10. Drug Delivery to Hypoxic Tumors Targeting Carbonic Anhydrase IX, Ahmed M. Shabana and Marc A. Ilies; Chapter 11. Light-Induced Reactive-Oxygen-Species- (ROS-) Mediated Activation of Self-Assembled Nanoplatforms for On-Demand Drug Delivery, Gurusamy Saravanakumar and Won Jong Kim; Chapter 12. Redox Polyion Complex Micelle-Based Injectable Hydrogel as Local Reactive Oxygen Species Scavenging Therapeutics, Long Binh Vong and Yukio Nagasaki; Chapter 13. Colon-Targeted Delivery Systems for Therapeutic Applications: Drug Release from Multiparticulate, Monolithic Matrix, and Capsule-Filled Delivery Systems, Safa Cyrus Fassihi, Rahmat Talukder, and Reza Fassihi; Editors Biographies; Indexes; Author Index; Subject Index;
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