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Genetic Analysis
Genes, Genomes, and Networks in Eukaryotes
9780199651818
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Description
How do we know what role a particular gene has? How do some genes control the expression of others? How do genes interact to form gene networks?With its unique integration of genetics and molecular biology, Genetic Analysis probes fascinating questions such as these, detailing how our understanding of key genetic phenomena can be used to understand biological systems. Opening with a brief overview of key genetic principles, model organisms, and epigenetics, the book goes on to explore the use of gene mutations and the analysis of gene expression and activity. A discussion of the genetic structure of natural populationsfollows, before the interaction of genes during suppression and epistasis, how we study gene networks, and personalized genomics are considered.Drawing on the latest experimental tools, including microarrays, RNAi screens, and bioinformatics approaches, Genetic Analysis provides a state-of-the-art review of the field, but in a truly student-friendly manner. It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research, without losing clarity of explanation and insight.We are in an age where, despite knowing so much about biological systems, we are just beginning to realise how much more there is still to understand. Genetic Analysis is the ideal guide to how we can use the awesome power of molecular genetics to further our understanding.Online Resource CentreThe Online Resource Centre to accompany Genetic Analysis features the following resources for teachers and students::For students::· Topical updates - key updates on topics or tools presented in the book, to keep you up-to-date with the latest developments in the field.· Additional case studies and text boxes to complement and add to those found in the book.· Practice problems, to test the readers knowledge of the concepts presented, and help to master them.For registered adopters of the book::· Figures from the book in electronic format, ready to download.· Journal clubs - suggested papers and discussion questions linked to topics covered in the book.
Product Details
87325
9780199651818
9780199651818
Data sheet
- Publication date
- 2014
- Issue number
- 2
- Cover
- paperback
- Pages count
- 580
- Dimensions (mm)
- 195 x 265
- Weight (g)
- 1206
- Unit I Genes, Chromosomes, and Genomes; The Logic of Genetic Analysis; Model Organisms and Their Genomes; Genomes, Chromosomes, and Epigenetics; Unit II Genes and Mutations; Identifying and Classifying Mutants; Connecting a Phenotype to a DNA Sequence; Finding Mutant Phenotypes for Cloned Genes; Genome-wide Mutant Screens; Unit III Genes and Natural Variation; Genome-wide Associations; Genetic Analysis of Complex Traits; Genetic Analysis Using Natural Variation; Unit IV Gene Interactions; Using One Gene to Identify Functionally Related Genes; Epistasis and Genetic Pathways; Pathways, Networks, and Systems; Genes, Systems, and Phenotypes;
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