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High-Yield⢠Cell and Molecular Biology
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This completely revised and updated review book consolidates the most important clinical issues that medical students need to know to be prepared for questions on USMLE Step 1. The book reviews key cell biology concepts needed to study molecular biology, and reviews the key concepts of molecular biology necessary for clinical medical practice, Flow charts provide a clear overview of molecular biology techniques and how they are applied in medicine. A chapter on understanding the research literature provides a solid background in molecular biology protocol so that students can understand the purpose and thinking behind published research articles.
Data sheet
- Publication date
- 2006
- Issue number
- 2
- Cover
- paperback
- Pages count
- 288
- Dimensions (mm)
- 178 x 254
- Weight (g)
- 454
- The Cell Membrane:: Eicosanoids and Receptors/Signal Transduction
I. The Lipid Component of the Cell Membrane
II. The Protein Component of the Cell Membrane
III. Membrane Transport Proteins
IV. G-Protein-Linked Receptors
V. Types of G-Protein-Linked Receptors
VI. Enzyme-Linked Receptors
VII. Low-Density Lipoprotein (LDL) Receptor
VIII. Summary Table
Cytoplasm and Organelles
I. Cytoplasm
II. Ribosomes
III. Rough Endoplasmic Reticulum
IV. Golgi Complex
V. Smooth Endoplasmic Reticulum (sER)
VI. Mitochondria
VII. Lysosomes
VIII. Peroxisomes
IX. Cytoskeleton
X. Cell Inclusions
XI. Selected Photomicrographs
Nucleus
I. Nuclear Envelope
II. Apoptosis
III. Nucleolus
IV. Assembly of the Ribosome
Protein Synthesis
I. General Features
II. Transcription
III. Processing the RNA Transcript into MRNA
IV. Translation
V. Clinical Considerations
Chromosomal DNA
I. The Biochemistry of Nucleic Acids
II. Levels of DNA Packaging
III. Centromere
IV. Heterochromatin and Euchromatin
V. Studying Human Chromosomes
VI. Staining of Chromosomes
VII. Chromosome Morphology
Numerical Chromosomal Anomalies
I. Polyploidy
II. Mixoploidy
III. Aneuploidy
IV. Selected Photographs
Structural Chromosomal Abnormalities
I. Deletions
II. Microdeletions
III. Translocations
IV. Unstable Expanding Repeat Mutations (Dynamic Mutations)
V. Isochromosomes
VI. Inversions
VII. Breakage
VIII. Selected Photographs
Chromosome Replication and DNA Synthesis
I. General Features
II. The Replication Process
III. The Telomere
IV. Types of DNA Damage and DNA Repair
V. Summary of DNA Replication Machinery
Meiosis and Genetic Recombination
I. Meiosis
II. Oogenesis:: Female Gametogenesis
III. Spermatogenesis:: Male Gametogenesis
IV. Genetic Recombination
The Human Nuclear Genome
I. General Features
II. Protein-Coding Genes
III. RNA-Coding Genes
IV. Epigenetic Control
V. Non-Coding DNA
The Human Mitochondrial Genome
I. General Features
II. Protein-Coding Genes
III. RNA-Coding Genes
IV. Other Mitochondrial Proteins
V. Mitochondrial Diseases
Control of Gene Expression
I. General Features
II. Mechanism of Gene Expression
III. The Structure of Transcription Factors, Gene Regulatory Proteins, and Other Trans-Acting Factors
IV. Clinical Considerations
V. Other Mechanisms of Gene Expression
VI. The lac Operon
VII. The trp Operon
Mutations of the DNA Sequence
I. General Features
II. Silent (Synonymous) Mutations
III. Non-Silent (Nonsynonymous) Mutations
IV. Loss of Function and Gain of Function Mutations
V. Other Types of Polymorphisms
Proto-Oncogenes, Oncogenes, and Tumor-Suppressor Genes
I. Definitions
II. Designations
III. Proto-Oncogenes and Oncogenes
IV. Tumor Suppressor Genes
V. Molecular Pathology of Colorectal Cancer
The Cell Cycle
I. Phases of the Cell Cycle
II. Control of the Cell Cycle
III. Stages of the M (Mitosis) Phase
Molecular Biology of Cancer
I. The Causes of Cancer
II. The Six Superpowers of a Cancer Cell
Homeotic Genes and Anterior/Posterior Body Pattern Formation
I. Introduction
II. Human Homeotic Genes
The Human Mitochondrial Genome
-
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