Total Intravenous Anaesthesia (TIVA) does not have to be complicated. This fully updated second edition translates TIVA into an engaging, and practical guide for anaesthesia practitioners at all levels. Written in clear, straightforward language and enriched with insights from international experts, the book covers everything from core principles to advanced techniques, including pharmacokinetic models, dosage calculations, and emergency applications. Featuring practical advice for treating a wide range of patients - from routine elective cases to paediatric, geriatric, obese, and pregnant individuals - making it an essential resource for safe, confident anaesthetic care. Including real-world examples, diagrams, and step-by-step evidence-based guidance on TIVA techniques, drug pharmacology, and protocols, the authors bring fresh perspectives and updated knowledge to reflect the latest research and innovations. Whether youre starting out or refining your skills, this handbook delivers the clarity, confidence, and practical guidance needed to master TIVA in everyday clinical settings - an essential companion.
Foreword to the first edition Iain Glen; Introduction Michael G. Irwin and Claire C. Nestor; 1. The advantages of TIVA Michael G. Irwin, Claire C. Nestor and Thomas Emms; 2. What is the Keo in pharmacokinetics and dynamics? Frank H. Engbers; 3. TCI for TIVA, what a good idea! A historical perspective of the development of TCI Michael G. Irwin and Gavin N. C. Kenny; 4. Propofol pharmacology Kane O. Pryor and Paul S. Myles; 5. Pharmacokinetics Douglas J. Eleveld; 6. TIVA safety - errors and solutions, tips and tricks Laura Flood and Robert James Fleming; 7. Processed EEG monitoring Mark Barley; 8. The role and effects of adjuvant medications Vivian Man Ying Yuen; 9. Preventative analgesia with total intravenous anesthesia John Pham, Kasi Goodwin and Alastair Moody; 10. Smooth recovery Anthony Ray Absalom and Johann Klaus Götz Wietasch; 11. TIVA in emergency surgery: delivering safe anaesthesia under pressure Andrew W. Smith, Claire C. Nestor and Michael G. Irwin; 12. Paediatric TIVA Brian Anderson; 13. TIVA in the elderly Musab Elhadi and Claire Frith-Keyes; 14. Extreme weights: the roller coaster of intravenous anaesthesia L. Ignacio Cortinez, Carolina Frederico and Brian J. Anderson; 15. TIVA in obstetrics Rosemarie Kearsley and Caoimhe Duffy; 16. Sustainability in total intravenous anaesthesia Rebecca Crosby, Peter Brooks, Li Fang and Clifford L. Shelton; 17. To infinity and beyond: the future of TIVA Michele Introna, Zahra Moaiyeri and Francisco A. Lobo; 18. Friend or foe: implications of anaesthesia on cancer surgery Eimear Keane, Dulmi Nawarathna and Thomas P. Wall; 19. TIVA in exceptional circumstances: TIVA in a pandemic and drug shortages Lauren M. Hughes, Claire C. Nestor and Michael G. Irwin; 20. TIVA for specific procedures and diseases Paul Andrew Stewart, Claire C. Nestor and Michael G. Irwin; 21. Emerging drugs for TIVA Madhumitha Gnanamoorthy, Claire C. Nestor and Michael G. Irwin; Index.
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