Bioinformatics:: Principles and Applications is a comprehensive text designed to cater to the needs of undergraduate and postgraduate students of biotechnology and bioinformatics. This book will also cater to the requirements of students pursuing short-term diploma as also DOEACC courses in bioinformatics. Beginning with the aim and scope of bioinformatics, the book discusses in detail the essentials of the subject, such as bio-algorithms, bio-databases, molecular viewers, gene annotation methods, molecular phylogeny, and bio-molecular simulations. It further discusses the applications of bioinformatics in protein modeling and computer-aided drug design. The book also presents a discussion on molecular docking, including guidelines for using AutoDock software. The usage of select bioinformaticscommercial software modules is also discussed. Written in a lucid style and user-friendly manner, the book with its wide and up to date coverage will be useful to students as well as practising professionals.
Preface; Part I: Introduction to Bioinformatics; A Word on Bioinformatics; Part II: Biological Databases; Sequence and Molecular File Formats; Databases in Bioinformatics - An Introduction; Biological Sequence Databases; Protein 3D Structure and Classification Databases; Part III: Bio-algorithms and Tools; Sequence Alignment; Gene Prediction Methods: Principles and Challenges; Molecular Phylogeny; Molecular Viewers; Part IV: Protein Modelling and Drug Design; Protein Structure and Modelling; Bioinformatics in Computer-aided Drug Design; Part V: Modelling of Biomolecular Systems; Simulation and Statistical Protocols; Biochemical Networks; Part VI: Bioinformatics Essentials; Commercial Bio-software; Appendix I: Perspectives of Emerging Research Areas in Bioinformatics - RNAi, Epigenetics, and Stem Cells; Appendix II: Bioinformatics Database Collection with their Websites and Descriptions; Appendix IV: Bio-companies and Bioinformatics-related Courses Available in India; Test Your Understanding; Glossary; Index;
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