Molecular Diagnostics: Fundamentals, Methods and Clinical Applications

Meet the challenges of this rapidly expanding field with a solid understanding of the fundamentals of nucleic acid biochemistry as well as the advanced concepts integral to practice in today’s laboratories. With a focus on the application of molecular concepts to the diagnosis of disease, the third edition of this popular resource encompasses microbiology, virology, genetics, oncology, and human identification. Inside, you’ll find in-depth explanations of the principles of molecular-based assays as well as reference material and trouble-shooting tips for the laboratory. Discussions of general diagnostic procedures prepare you to adapt to the emergence of new diagnostic technologies. Coverage of the application of molecular diagnostics to the clinical laboratory encompass microbiology, virology, genetics, oncology, and human identification. A visually rich art program makes concepts crystal clear with line drawings, flow charts, and photographs. Objectives guide the reader toward the knowledge that should be gained upon completion of each chapter. “Advanced Concepts” appear in boxes throughout the text to challenge those students interested in a higher level of learning. “Historical Highlights” enable interested students to apply a historical perspective to the topics. “Case Studies” in the clinical chapters show students how to apply molecular concepts to diagnostic testing. Key Terms are bolded and defined within the text where they first appear. Study Questions at the end of each chapter reinforce the content. Answers, included in the appendix, allow for self assessment outside of the classroom. Citations of seminal publications encourage the interested student to read and pursue at greater depth the various topics discussed.