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Goldfrank's Toxicologic Emergencies, Ninth Edition

Goldfrank's Toxicologic Emergencies, Ninth Edition

9780071605939
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Description

The most trusted, rigorous, and up-to-date toxicology resource and educational companion available – now in full color

A Doodys Core Title ESSENTIAL PURCHASE for 2011!

Goldfranks Toxicologic Emergencies continues to be the source you can turn to first for any poisoning or overdose. The text provides clear information on every aspect of toxicologic emergencies, from pharmacology to clinical presentation to management.

Fully referenced and featuring a consistent organization, Goldfranks begins with an in-depth examination of general principles of medical toxicology. It then progresses to the biochemical principles and molecular basis of toxicology, and provides detailed insight into how xenobiotics affect vital signs, organs, and systems throughout the body. Next, a wide spectrum of clinically important exposures -- including drugs, plants, metals, household products, occupational and environmental xenobiotics are covered within logical categories for easy access to information. Finally, the book concludes with sections on principles of practicing clinical toxicology in todays challenging healthcare environment.

NEW TO THIS EDITION

  • Full-color design and uniformly drawn figures clarify key concepts
  • Special Considerations focus on decision-making in unique toxicologic circumstances, that influence clinical practice and have the potential to improve patient care
  • Antidotes in Depth, following pertinent chapters, place each antidote in its proper context to ensure immediate availability of essential information relevant for clinical use
  • More clinically-relevant figures and quick-reference tables
  • Online learning center, available at www.goldfrankstoxicology.com, includes case studies, and a database of multiple choice questions that allow you to create a custom test for review and study.
  • Every chapter is thoroughly rewritten and new chapters are added to reflect the very latest thinking in the field
Product Details
McGraw Hill / Medical
49164
9780071605939
9780071605939

Data sheet

Publication date
2010
Issue number
9
Cover
hard cover
Pages count
1968
Dimensions (mm)
224 x 285
Weight (g)
4072
  • Table of Antidotes in Depth
    Contributors
    Preface
    Acknowledgments
    1. Historical Principles and Perspectives, Paul M. Wax
    2. Toxicologic Plagues and Disasters in History, Paul M. Wax
    PART A:: THE GENERAL APPROACH TO MEDICAL TOXICOLOGY
    3. Initial Evaluation of the Patient:: Vital Signs and Toxic Syndromes, Lewis S. Nelson, Neal A. Lewin, Mary Ann Howland, Robert S. Hoffman, Lewis R. Goldfrank, and Neal F. Flomenbaum
    4. Principles of Managing the Acutely Poisoned or Overdosed Patient, Lewis S. Nelson, Neal A. Lewin, Mary Ann Howland, Robert S. Hoffman, Lewis R. Goldfrank, and Neal F. Flomenbaum
    5. Diagnostic Imaging, David T. Schwartz
    6. Laboratory Principles, Petrie M. Rainey
    7. Techniques Used to Prevent Gastrointestinal Absorption, Anne-Bolette J. Christophersen and Lotte C.G. Hoegberg
    A1. Syrup of Ipecac, Mary Ann Howland
    A2. Activated Charcoal, Mary Ann Howland
    A3. Whole-Bowel Irrigation and Other Intestinal Evacuants, Mary Ann Howland
    8. Pharmacokinetic and Toxicokinetic Principles, Mary Ann Howland
    9. Principles and Techniques Applied to Enhance Elimination, David S. Goldfarb
    10. Use of The Intensive Care Unit, Mark A. Kirk
    PART B:: THE FUNDAMENTAL PRINCIPLES OF MEDICAL TOXICOLOGY
    Section 1:: Biochemical and Molecular Basis
    11. Chemical Principles, Stephen J. Traub and Lewis S. Nelson
    12. Biochemical and Metabolic Principles, Kurt C. Kleinschmidt and Kathleen A. Delaney
    13. Neurotraansmitters and Neuromodulators, Steven C. Curry, Kirk C. Mills, Anne-Michalle Ruha, and Ayrn D. OConnor
    14. Withdrawal Principles, Richard J. Hamilton
    Section 2:: Pathophysiologic Basis:: Organ Systems
    15. Thermoregulatory Principles, Susi U. Vassallo and Kathleen A. Delaney
    16. Fluid, Electrolyte, and Acid-Based Principles, Alan N. Charney and Robert S. Hoffman
    17. Psychiatric Principles, Kishor Malavade and Mark R. Serper
    18. Neurologic Principles, Rama B. Rao
    19. Ophthalmic Principles, Adhi Sharma
    20. Otolaryngologic Principles, William K. Chiang
    21. Respiratory Principles, Andrew Stolbach and Robert S. Hoffman
    22. Electrophysiologic and Electrocardiographic Principles, Cathleen Clancy
    23. Hemodynamic Principles, Robert A. Hessler
    24. Hematologic Principles, Marco L.A. Sivilotti
    25. Gastrointestinal Principles, Richard J. Church and Kavita M. Babu
    26. Hepatic Principles, Kathleen A. Delaney
    27. Renal Principles, Donald A. Feinfeld and Nikolas B. Harbord
    28. Genitourinary Principles, Jason Chu
    29. Dermatologic Principles, Neal A. Lewin and Lewis S. Nelson
    Section 3:: Special Populations
    30. Reproductive and Perinatal Principles, Jeffrey S. Fine
    31. Pediatric Principles, Jeffrey S. Fine
    32. Geriatric Principles, Judith C. Ahronheim and Mary Ann Howland
    33. Postmortem Toxicology, Rama B. Rao and Mark Flomenbaum
    SC1. Organ Procurement from Poisoned Patients, Rama B. Rao
    PART C:: THE CLINICAL BASIS OF MEDICAL TOXICOLOGY
    Section 1:: Case Studies
    A. Analgesics and Antiinflammatory Medications
    34. Acetaminophen, Robert G. Hendrickson
    A4. N-Acetylcysteine, Mary Ann Howland and Robert G. Hendrickson
    35. Salicylates, Neal E. Flomenbaum
    A5. Sodium Bicarbonate, Paul M. Wax
    36. Nonsteroidal Antiinflammatory Drugs, William J. Holubek
    37. Colchicine, Podophyllin, and the Vinca Alkoloids, Joshua G. Schier
    SC2. Intrathecal Administration of Xenobiotics, Rama B. Rao
    38. Opioids, Lewis S. Nelson and Dean Olsen
    A6. Opioid Antagonists, Mary Ann Howland and Lewis Nelson
    B. Foods, Dietary and Nutritional Agents
    39. Dieting Agents and Regimens, Jeanna M. Marraffa
    40. Iron, Jeanmarie Perrone
    A7. Deferoxamine, Mary Ann Howland
    41. Vitamins, Beth Y. Ginsburg
    42. Essential Oils, S. Eliza Halcomb
    43. Herbal Preparations, Oliver L. Hung
    44. Athletic Performance Enhancers, Susi U. Vassallo
    45. Food Poisoning, Michael G. Tunik
    46. Botulism, Howard L. Geyer
    A8. Botulinum Antitoxin, Lewis R. Goldfarb and Howard L. Geyer
    C. Pharmaceuticals
    47. Anticonvulsants, Suzanne Doyon
    A9. L-Carnitine, Mary Ann Howland
    48. Antidiabetics and Hypoglycemics, George M. Bosse
    A10. Dextrose, Larissa I. Velez and Kathleen A. Delaney
    A11. Octreotide, Mary Ann Howland
    49. Thyroid and Antithyroid Medications, Nicole C. Bouchard
    50. Antihistamines and Decongestants, Anthony J. Tomassoni and Richard S. Weisman
    A12. Physostigmine Salicylate, Mary Ann Howland
    51. Antimigraine Medications, Jason Chu
    52. Antineoplastics Overview, Richard Y. Wang
    53. Antineoplastics:: Methotrexate, Richard Y. Wang
    A13. Leucovorin (Folinic Acid) and Folic Acid, Mary Ann Howland
    A14. Glucarpidase, (Carboxypeptidas G2), Silas W. Smith
    SC3. Extravasation of Xenobotics, Richard Y. Wang
    54. Miscellaneous Antineoplastics, Richard Y. Wang
    55. Pharmaceutical Additives, Sean P. Nordt and Lisa E. Vivero
    D. Antimicrobials
    56. Antibacterials, Antifungals, and Antivirals, Christine M. Stork
    57. Antituberculous Medications, Christina H. Hernon and Edward W. Boyer
    58. Antimalarials, J. Dave Barry
    E. Cardiopulmonary Medications
    59. Anticoagulants, Mark Su
    A16. Vitamin K, Mary Ann Howland
    A17. Protamine, Mary Ann Howland
    60. Calcium Channel Blockers, Francis DeRoos
    A18. Insulin-Eyglycemia Therapy, William Kerns II
    61. B-Adrenergic Antagonists, Jeffrey R. Brubacher
    A19. Glucagon, Mary Ann Howland
    62. Other Antihypertensives, Francis DeRoos
    63. Antidysrhythmics, Lewis S. Nelson and Neal A. Lewin
    64. Cardioactive Steroids, Jason B. Hack
    A20. Digoxin-Specific Antibody Fragments, Mary Ann Howland
    65. Methylxanthines and Selective B2 Adrenergic Agonists, Robert J. Hoffman
    F. Anesthetics and Related Medications
    66. Local Anesthetics, David R. Schwartz and Brian Kaufman
    A21. Intravenous Fat Emulsions, Todd Bania
    67. Inhalational Anesthetics, Brian Kaufman and Martin Griffel
    68. Neuromuscular Blockers, Kenneth M. Sutin
    A22. Dantrolene Sodium, Kenneth M. Sutin
    G. Psychotropic Medications
    69. Antipsychotics, David Juurlink
    70. Lithium, Howard A. Greller
    71. Monoamine Oxidase Inhibitors, Alex F. Manini
    72. Serotonin Reuptake Inhibitors and Atypical Antidepressants, Christine M. Stork
    73. Cyclic Antidepressants, Erica L. Liebelt
    74. Sedative-Hynotics, David C. Lee and Kathy Ferguson
    A23. Flumazenil, Mary Ann Howland
    H. Substances of Abuse
    75. Amphetamines, William K. Chiang
    76. Cocaine, Jane M. Prosser and Robert S. Hoffman
    SC4. Internal Concealment of Xenobiotics, Jane M. Prosser
    A24. Benzodiazepines, Robert S. Hoffman, Lewis S. Nelson, and Mary Ann Howland
    77. Ethanol, Luke Yip
    A25. Thiamine Hydrochloride, Robert S. Hoffman
    78. Ethanol Withdrawal, Jeffrey Gold and Lewis S. Nelson
    79. Disulfiram and Disulfiram-Like Reactions, Edwin K. Kuffner
    80. Y-Hydroxybutyric Acid, Brenna M. Farmer
    81. Inhalants, Heather Long
    82. Hallucinogens, Kavita M. Babu
    83. Cannabinoids, Michael A. McGuigan
    84. Nicotine, Sari Soghoian
    85. Phencyclidine and Ketamine, Ruben Olmedo
    86. Aluminum, Brenna M. Farmer
    I. Metals
    87. Antimony, Asim F. Tarabar
    88. Arsenic, Stephen W. Munday and Marsha Ford
    A26. Dimercaprol (British Anti-Lewisite or Bal), Mary Ann Howland
    89. Bismuth, Rama B. Rao
    90. Cadmium, Stephen J. Traub and Robert s. Hoffman
    91. Chromium, Steven B. Bird
    92. Cobalt, Gar Ming Chan
    93. Copper, Lewis S. Nelson
    94. Lead, Fred M. Henretig
    A27. Succimer (2,3-Dimercaptosuccinic Acid), Mary Ann Howland
    A28. Edetate Calcium Disodium (CaNa2EDTA), Mary Ann Howland
    95. Manganese, Sari Soghoian
    96. Mercury, Young-Jin Sue
    97. Nickel, John Curtis and David A. Haggerty
    98. Selenium, Diane P. Calello
    99. Silver, Melisa W. Lai Becker and Michele Burns Ewald
    100. Thallium, Maria Mercurio and Robert S. Hoffman
    A29. Prussian Blue, Robert S. Hoffman
    101. Zinc, Nima Majlesi
    J. Household Products
    102. Antiseptics, Disinfectants, and Sterilants, Paul M. Wax
    103. Camphor and Moth Repellents, Edwin K. Kuffner
    104. Caustics, Jessica A. Fulton
    105. Hydrofluoric Acid and Fluorides, Mark Su
    A30. Calcium, Mary Ann Howland
    106. Hydrocarbons, David D. Gummin
    107. Toxic Alcohols, Sage W. Wiener
    SC5. Diethylene Glycol, Joshua G. Schier
    A31. Fomepizole, Mary Ann Howland
    A32. Ethanol, Mary Ann Howland
    K. Pesticides
    108. Pesticides:: An Overview with a Focus on Principles and Rodenticides, Neal F. Flomenbaum
    109. Barium, Andrew Dawson
    110. Sodium Monofluoroacetate and Fluroacetamide, Fermin Barrueeto Jr.
    111. Phosphorus, Michael Beuhler
    112. Strychnine, Yiu-Cheung Chan
    113. Insecticides:: Organic Phosphorus Compounds and Carbamates, Michael Eddleston and Richard F. Clark
    A33. Pralidoxmine, Mary Ann Howland
    A34. Atropine, Mary Ann Howland
    114. Insecticides:: Organic Chlorines, Pyrethrins/Pyrethroids, and Insect Repellents, Michael G. Holland
    115. Herbicides, Darren M. Roberts
    116. Methyl Bromide and Other Fumigants, Keith K. Burkhart
    L. Natural Toxins and Envenomations
    117. Mushrooms, Lewis R. Goldfrank
    118. Plants, Mary Palmer and Joseph M. Betz
    119. Arthropods, In-Hei Hahn
    A35. Antivenom (Scorpion and Spider), Richard F. Clark
    120. Marine Envenomations, D. Eric Brush
    121. Snakes and Other Reptiles, Bradley D. Riley, Anthony F. Pizon, and Anne-Michelle Ruha
    A36. Antivenom (Crotaline and Elapid), Anthony F. Pizon, Bradley D. Riley, and Anne-Michelle Ruha
    M. Occupational and Environmental Toxins
    122. Industrial Poisoning:: Information and Control, Peter H. Wald
    123. Nanotoxicology, Silas W. Smith
    124. Simple Asphyxiants and Pulmonary Irritants, Lewis Nelson and Oladapo Obujebe
    125. Carbon Monoxide, Christian Tomaszewski
    A37. Hyperbaric Oxygen, Stephen R. Thom
    126. Cyanide Andhydrogen Sulfide, Christopher P. Hostege, Gary E. Isom, and Mark A. Kirk
    A38. Sodium and Amyl Nitrites, Mary Ann Howland
    A39. Sodium Thiosulfate, Mary Ann Howland
    A40. Hydroxocobalamin, Mary Ann Howland
    127. Methemoglobin Inducers, Dennis P. Price
    A41. Methylene Blue, Mary Ann Howland
    128. Smoke Inhalation, Nathan Charlton and Mark A. Kirk
    N. Disaster Preparedness
    129. Risk Assessment and Risk Communications, Charles McKay, Jr.
    130. Hazmat Incident Response, Bradley Kaufman
    131. Chemical Weapons, Jeffrey R. Suchard
    132. Biological Weapons, Jeffrey R. Suchard
    133. Radiation, Joseph Rella
    A42. Potassium Iodide, Joseph Rella
    A43. Pentetic Acid (Dtpa) or Pentetate (Zinc or Calcium) Trisodium, Joseph Rella
    Section 2:: Poison Centers and Epidemiology
    134. Poison Prevention and Education, Lauren Schwartz
    135. Poison Centers and Poison Epidemiology, Robert S. Hoffman
    136. International Perspectives on Toxicology, Michael Eddleston
    137. Principles of Epidemiology and Research Design, Kevin C. Osterhoudt
    138. Adverse Drug Events and Postmarketing Surveillance, Louis R., Cantilena
    139. Medication Safety and Adverse Drug Events, Brenna M. Farmer
    140. Risk Management and Legal Principles, Barbara M. Kirrane and Dainius A. Drukteinis
    Index
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