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Middleton's Allergy 2-Volume Set

Middleton's Allergy 2-Volume Set

Principles and Practice

9780443249723
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2026-02-09

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Description
As both a practical reference for clinicians and researchers and an effective self-assessment tool for board preparation, Middletons Allergy:: Principles and Practice remains the #1 authoritative resource in the field. This fully revised 10th Edition brings you up to date with recent advancements in basic science and clinical applications regarding allergy practice and disease mechanisms, offering unparalleled guidance on the full spectrum of allergy across the lifespan.
Product Details
Elsevier
104327
9780443249723
9780443249723

Data sheet

Publication date
2026
Issue number
10
Cover
hard cover
Pages count
1840
Dimensions (mm)
216 x 276
Weight (g)
450
  • SECTION A: Basic Sciences Underlying Allergy and Immunology
    1. Innate Immunity
    2. Adaptive Immunity
    3. Immunoglobulin Structure and Function
    4. Immune Tolerance
    5. Cytokines in Allergic Inflammation
    6. Cellular Adhesion in Inflammation
    7. Chemokines
    8. The Complement System
    9. Lipid Mediators of Hypersensitivity and Inflammation
    10. Molecular Biology and Genetic Engineering
    11. Biology of Lymphocytes
    12. Innate Lymphoid Cells
    13. Antigen-Presenting Dendritic Cells
    14. Biology of Mast Cells and Their Mediators
    15. Biology of Basophils
    16. Biology of Eosinophils
    17. Biology of Neutrophils
    18. Biology of Monocytes and Macrophages
    19. Airway Epithelial Cells
    20. Airway Smooth Muscle in Asthma
    21. Pathophysiology of Allergic Inflammation
    22. Genetics and Epigenetics in Allergic Diseases
    23. Omic and Systems Biology Approaches to Allergic Disease
    24. Immunobiology of IgE and IgE Receptors
    25. Neuronal Control of Airway Function in Allergy

    SECTION B: Aerobiology and Allergens
    26. The Structure and Function of Allergens
    27. Aerobiology of Outdoor Allergens
    28. Indoor Allergens
    29. Preparation and Standardization of Allergens and Allergen Extracts
    30. Air Pollution: Indoor and Outdoor

    SECTION C: The Skin
    31. Structure of the Skin and Cutaneous Immunology
    32. Atopic Dermatitis
    33. Contact Dermatitis
    34. Urticaria and Angioedema
    35. Hereditary Angioedema and Bradykinin-Mediated Angioedema
    36. Immune Complexes in Disease

    SECTION D: The Eye
    37. Allergic Diseases of the Eye

    SECTION E: Respiratory Tract
    38. The Nose and Control of Nasal Airflow
    39. Allergic and Nonallergic Rhinitis
    40. Rhinosinusitis and Nasal Polyps
    41. Development, Structure, and Physiology in Normal Lung and in Asthma
    42. Respiratory Tract Mucosal Immunology
    43. Airway Mucus and the Mucociliary System
    44. Epidemiology of Asthma and Allergic Diseases
    45. Ontogeny of Immune Development and Its Relationship to Allergic Diseases and Asthma
    46. Climate Change: Allergic Diseases and Asthma
    47. Mouse Models of Allergic Airways Disease
    48. Diagnosis of Asthma in Infants and Children
    49. Management of Asthma in Infants and Children
    50. Diagnosis of Asthma in Adults
    51. Management of Asthma in Adolescents and Adults
    52. Emergency Treatment and Approach to the Patient with Acute Asthma
    53. Approach to the Patient with Exercise-Induced Bronchoconstriction
    54. Asthma and Allergic Diseases during Pregnancy
    55. Occupational Allergy and Asthma
    56. Pathology of Asthma
    57. Allergic Bronchopulmonary Aspergillosis, Hypersensitivity Pneumonitis and Epidemic Thunderstorm Asthma
    58. Immunologic Nonasthmatic Diseases of the Lung
    59. Approaches to the Patient with Chronic Cough
    60. Bronchial and Nasal Challenge Testing
    61. Lung Imaging
    62. Aerosols and Aerosol Drug Delivery Systems

    SECTION F: Gastrointestinal Tract
    63. Gastrointestinal Mucosal Immunology
    64. Eosinophilic Gastrointestinal Disorders

    SECTION G: Systemic Disease
    65. Clinical Significance of Immunoglobulin E
    66. In Vivo Methods for the Study and Diagnosis of IgE-mediated Allergy
    67. Approach to the Patient with Recurrent Infections
    68. Primary Immunodeficiency Diseases
    69. Treatment of Primary Immunodeficiency Diseases
    70. HIV Infection and Allergic Disease
    71. Laboratory Tests for Allergic and Immunodeficiency Diseases
    72. Eosinophilia and Eosinophil-Related Disorders
    73. Mastocytosis
    74. Anaphylaxis
    75. Insect Allergy
    76. Drug Allergy
    77. Hypersensitivity to Aspirin and Other Nonsteroidal Antiinflammatory Drugs
    78. Reactions to Foods
    79. Oral Food Challenge Testing
    80. Food Allergy Management, Prevention and Therapy
    81. Adverse Reactions to Vaccines

    SECTION H: Therapeutics
    82. Allergen Immunotherapy for Inhalant Allergens
    83. Principles of Pharmacotherapeutics
    84. Precision Medicine in Allergic Disorders
    85. Optimizing Adherence in Practice
    86. Anti-Immunoglobulin E Therapy
    87. Cytokine-Specific Therapy in Asthma
    88. Histamine and Antihistamines
    89. Inhaled ?2-Agonists
    90. Anticholinergic Therapies
    91. Glucocorticoids
    92. Antileukotriene Therapy in Asthma
    93. Unconventional Theories and Unproven Methods in Allergy
    94. Complementary and Integrative Health

    APPENDIX A: CD Molecules
    (E-ONLY) Answers to Self-Assessment Questions
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