In this issue of Rheumatic Disease Clinics, guest editors Drs. Seth E. Kaplan and Rula Hajj-Ali bring their considerable expertise to the topic of ENT Manifestations in Rheumatology. Common presentations include chronic sinusitis, hearing loss, hoarseness, nasal crusting, recurrent ear infections, and dry mouth. This issue provides guidance in the crucial area of early recognition of ENT symptoms, as they may be initial indicators of systemic disease and timely diagnosis can prevent serious complications and improve outcomes.