In this issue of Clinics in Perinatology, guest editors Drs. Andrea C. Pardo, Niranjana Natarajan, and Laura Vernon bring their considerable expertise to the topic of Neonatal Neurocritical Care. Top experts focus on “must know” topics in neonatal neurocritical care for neonatologists practicing in all levels of complexity. The issue covers high-yield topics including current advances in the field, a glimpse into what is coming down the road and considerations for practice of neonatal neurocritical care around the world.