In this issue of Cardiac Electrophysiology Clinics, guest editors Drs. Ali R. Keramati and Mohammadali Habibi bring their considerable expertise to the topic of Advances in Antiarrhythmic Drug Therapy. Advances in antiarrhythmic drug therapy have led to significant progress in the management of cardiac arrhythmias, offering clinicians a range of medications to effectively treat and control irregular heart rhythms. The development of new drug classes and improved understanding of their mechanisms of action have enhanced patient outcomes and provided more personalized treatment options. In this issues, top experts explore key topics in this area of cardiac electrophysiology.