Veterinary Clinical Immunology

List of Contributors vii

Preface x

About the Companion Website xi

Section 1 A Primer for the Clinician 1

1 A Clinician’s Guide to the Immune System: Innate and Adaptive Immunity 3
Oliver A Garden

2 Pathophysiology of Immune- Mediated Disease 39
James W Swann

3 Immunogenetics: The Final Frontier 61
Lucy Davison and Lorna J Kennedy

4 Vector- Borne Pathogens and Immune- Mediated Disease 84
Linda Kidd and Edward B Breitschwerdt

Section 2 Diagnostic Approaches and Treatment 107

5 Diagnosing Immune- Mediated Disease: General Approach and Specific Tests 109
Linda Kidd and Amy L MacNeill

6 Treating Immune- Mediated Disease: What to Use and When 134
Todd M Archer and Claire L Fellman

Section 3 Specific Immune- Mediated Diseases 165

7 Blood and Hematopoietic System 167
Todd M Archer

8 Musculoskeletal System 192
Karen Perry

9 Central and Peripheral Nervous System 234
Nicolas Granger and Linda Kidd

10 Urinary Tract 279
Jack S Lawson and Harriet M Syme

11 Oral Cavity and Gastrointestinal Tract 313
Karin Allenspach, Al Jergens, Laura van Vertloo, and Brenda Mulherin

12 Liver, Biliary Tract, and Exocrine Pancreas 347
Penny Watson, Nick Bexfield, and Michael J Day

13 Nose, Trachea, and Bronchopulmonary System 387
Leah A Cohn, Cécile Clercx, and Michael J Day

14 Endocrine Organs 421
Lucy J Davison

15 Skin 436
Domenico Santoro

16 Eye and Adnexa 469
Marian Matas Riera and Oliver A Garden

17 Polysystemic Autoinflammatory and Autoimmune Diseases 503
Jonathan E Fogle

Section 4 Immunodeficiency, Onco-Immunology, and Vaccination 521

18 Primary Immunodeficiencies 523
James W Swann

19 Cancer Immunology 549
David Killick

20 Vaccination 580
Alison Stickney and NJ Cave

Index 615