In this issue of Otolaryngologic Clinics, guest editors Drs. Corinna G. Levine and Christine T. Dinh bring their considerable expertise to the topic of Cerebrospinal Fluid Leaks. Top experts provide a comprehensive review of anterior and lateral skull base CSF leaks, focusing on their causes, diagnosis, and clinical presentation. They also discuss management strategies for CSF leaks, including work-up, monitoring, and treatment options, as well as the emerging pathophysiology of CSF leaks and the latest advancements and trends in CSF leak management.