Oxford Textbook of Medicine

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Wydawca: OUP Oxford

ISBN: 9780198746690

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Opis

The Oxford Textbook of Medicine is the foremost international textbook of medicine. Unrivalled in its coverage of the scientific aspects and clinical practice of internal medicine and its subspecialties, it is a fixture in the offices and wards of physicians around the world, as well as being a key resource for medico-legal practitioners. Accessible digitally with regular updates, as well as in print, readers are provided with multiple avenues of access depending on theirneed and preference. More comprehensive, more authoritative, and more international than any other textbook; Oxford Textbook of Medicine focuses on offering both perspective and practical guidance on clinical management and prevention of disease. Introductory sections focus on the patient experience, medical ethics and clinical decision making, outlining a philosophy which has always characterized the Oxford Textbook of Medicine. It is humane, thought-provoking, and aims to instill in readers an understanding of the role of medicine in society and the contribution it can make to the health of populations, and it does not shy away from discussion of controversial aspects of modern medicine. As always, there is detailed coverage of all areas of internal medicine by the worlds very best authors. The Oxford Textbook of Medicine seeks to embody advances in understanding and practice that have arisen through scientific research. The integration of basic science and clinical practice is unparalleled, and throughout the book the implications of research for medical practice are explained. The core clinical medicine sections offer in-depth coverage of the traditional specialtyareas. The Oxford Textbook of Medicine has unsurpassed detail on infectious diseases:: the most comprehensive coverage to be found in any textbook of medicine. Other sections of note include stem cells and regenerative medicine; inequalities in health; medical aspects of pollution and climate change; traveland expedition medicine; bioterrorism and forensic medicine; pain; medical disorders in pregnancy; nutrition; and psychiatry and drug related problems in general medical practice. The section on acute medicine is designed to give rapid access to information when it is needed quickly. In response to ongoing user feedback there have been substantial changes to ensure that the Oxford Textbook of Medicine continues to meet the needs of its readers. Chapter essentials give accessible overviews of the content and a new design ensures that the textbook is easy to read and navigate. The evidence-base and references continue to be at the forefront of research. New to this edition is that purchasers of the print version of the Oxford Textbook of Medicine sixth edition will have free access on Oxford Medicine Online to all the content plus regular updates for the life of the edition.

Szczegóły produktu

Wydawca OUP Oxford

Indeks 86929

EAN13 9780198746690

ISBN 9780198746690

Opis

Rok wydania: 2020
Numer wydania: 6
Liczba stron: 7728
Wymiary (mm): 219 x 276
Waga (g): 18180

Section 1 - Patients and their treatment; An older patients story; A younger patients experience of healthcare; The patient in control; What do patients need?; Medical ethics; Principles of clinical decision making; Section 2 - Background to medicine; Science in medicine:: when, how, and what; Evolutionary medicine; The global burden of disease; Large-scale randomized evidence:: trials and meta-analyses of trials; Bioinformatics; Clinical Pharmacology; Biological Therapies in rheumatic diseases; Traditional Medicine exemplified by Traditional Chinese Medicine; Engaging patients in therapeutic development; Medicine quality, physicians and patients; Preventive medicine; Medical screening; Health promotion; Deprivation and health; How much should rich country governments spend on healthcare?; Financing healthcare in low- income developing countries:: A challenge for equity in health; Research in the developed world; Fostering medical and health research in resource-constrained countries; Regulation versus innovation in medicine; Human disasters; Humanitarian medicine; Complementary and Alternative medicine; Section 3 - Cell biology; The cell; The genomic basis of medicine; Cytokines; Ion channels and disease; Intracellular signalling; Apoptosis in health and disease; Stem cells and regenerative medicine; The evolution of therapeutic antibodies; Circulating DNA for molecular diagnostics; Section 4 - Immunological mechanisms; The innate immune system; The complement system; Adapative immunity; Immunodeficiency; Allergy; Autoimmunity; Principles of transplantation immunology; Section 5 - Principles of clinical oncology; Epidemiology of cancer; The nature and development of cancer:: cancer mutations and their implications; The genetics of inherited cancers; Cancer immunity and immunotherapy; Clinical features and management; Systemic treatment and radiotherapy; Medical management of breast cancer; Section 6 - Old age medicine; Ageing and clinical medicine; Frailty and sarcopenia; Optimising well being into old age; Older people and acute medical illness; Age atuning general hospital services; Supporting older peoples care in other specialist services; Drugs and prescribing; Falls, Faints and Fragility Fractures; Bladder and bowels; Neurodegenerative disorders in older people; Promotion of healthy living, dignity and quality of life; Section 7 - Pain & Pallative Care; Introduction to palliative care; Pain management; Management of other symptoms; Care of the dying person; Section 8 - Infectious diseases; Biology of pathogenic microorganisms; Clinical features and general management of patients with severe infections; Clinical approach to patient with suspected infection; Fever of unknown origin; Nosocomial infection; Infection in the immunocompromised host; Antimicrobial chemotherapy; Immunization; Travel & expedition medicine; Respiratory tract viruses; Herpesviruses (excluding Epstein Barr virus); Epstein-Barr virus; Poxviruses; Mumps:: epidemic parotitis; Measles; Nipah and Hendra virus encephalitides; Enterovirus infections; Virus infections causing diarrhoea and vomiting; Rhabdoviruses:: rabies and rabies-related lyssaviruses; Colorado tick fever & other arthropod-borne reoviruses; Alphaviruses; Rubella; Flaviviruses (excepting Dengue); Dengue; Bunyaviridae; Arenaviruses; Filoviruses; Papovaviruses and polyomaviruses; Parvovirus B19; Hepatitis viruses (excluding hepatitis C virus); Hepatitis C virus; HIV and AIDS; HIV in low- and middle-income countries; HTLV-1, HTLV-2 and associated diseases; Viruses and cancer; Orf and Milker s Nodule; Molluscum contagiosum; Newly discovered viruses; Diphtheria; Streptococci and enterococci; Pneumococcal infections; Staphylococci; Meningococcal infections; Neisseria gonorrhoeae; Enterobacteria and bacterial food-poisoning; Pseudomonas aeruginosa; Typhoid and paratyphoid fevers; Intracellular klebsiella infections (donovanosis and rhinoscleroma); Anaerobic bacteria; Cholera; Haemophilus influenzae; Haemophilus ducreyi & chancroid; Bordetella infection; Melioidosis & glanders; Plague:: Yersinia pestis; Other Yersinia infections - yersiniosis; Pasteurella; Francisella tularensis infection; Anthrax; Brucellosis; Tetanus; Clostridium difficile; Botulism, gas gangrene, and clostridial gastrointestinal infections; Tuberculosis; Disease caused by environmental mycobacteria; Leprosy (Hansens disease); Buruli ulcer:: Mycobacterium ulcerans infection; Actinomycosis; Nocardiosis; Rat bite fevers (Streptobacillus moniliformis and Spirillum minus infection); Lyme borreliosis; Relapsing fevers; Leptospirosis; Nonvenereal endemic treponematoses:: yaws, endemic syphilis (bejel), and pinta; Syphilis; Listeriosis; Legionelleosis and legionnaires disease; Rickettsiosis; Scrub typhus; Coxiella burnetti infections (Q fever); Bartonelloses, excluding B bacilliformis; Bartonella bacilliformis infection; Chlamydial infections; Mycoplasmas; A checklist of bacteria associated with infection in humans; Fungal infections; Cryptococcosis; Coccidioidomycosis; Paracoccidioidomycosis; Pneumocystis jiroveci; Taralomyces (Penicillium) marneffei infection; Microsporidiosis; Amoebic infections; Malaria; Babesiosis; Toxoplasmosis; Cryptosporidium and cryptosporidiosis; Cyclospora and cyclosporiasis; Cystoisospora; Sarcocystosis (sarcosporidiosis); Giardiasis and balantidiasis; Blastocystis infection; Human African trypanosomiasis; Chagas disease; Leishmaniasis; Trichomoniasis; Cutaneous filariasis; Lymphatic filariasis; Guinea worm disease (dracunculiasis); Strongyloidiasis, hookworm & other gut strongyloid nematodes; Gut and tissue nematode infections acquired by ingestion; Angiostrongylus; Cestodes (tapeworms); Cystic hydatid disease (Echinococcus granulosus); Cysticercosis; Schistosomiasis; Liver fluke infections; Lung flukes (paragonimiasis); Intestinal trematode infections; Non-venomous arthropods; Pentostomiasis (porocephalosis, linguatulosis/ linguatuliasis or tongue worm infection); Section 9 - Sexually transmitted diseases; Epidemiology of sexually transmitted diseases; Sexual behaviour; Sexual history and examination; Vaginal discharge; Urethritis; Ano-genital ulcers; Ano-genital lumps; Pelvic inflammatory disease; Principles of contraception; Section 10 - Environmental medicine, occupational medicine, and poisoning; Introduction; Occupational and environmental health; Occupational safety; Aviation medicine; Diving medicine; Noise; Vibration; Air pollution; Heat; Cold; Drowning; Lightning and electrical injuries; Diseases of high terrestrial altitudes; Radiation; Disasters:: earthquakes, volcanic eruptions, hurricanes & floods; Bioterrorism; Poisoning by drugs and chemicals; Injuries, envenoming, poisoning, allergic reactions caused by animals; Poisonous fungi; Poisonous plants; Section 11 - Nutrition; Macronutrient metabolism; Vitamins; Minerals and trace elements; Severe malnutrition; Diseases of affluent societies and the need for dietary change; Obesity; Artificial nutrition support; Section 12 - Metabolic disorders; The inborn errors of metabolism - general aspects; Protein-dependent Inborn errors of metabolism; Glycogen storage diseases; Inborn errors of fructose metabolism; Disorders of galactose, pentose, and pyruvate metabolism; Disorders of purine and pyrimidine metabolism; The porphyrias; Lipid and lipoprotein disorders; Hereditary haemochromatosis; Inherited diseases of copper metabolism:: Wilsons Disease and Menkes Disease; Lysosomal disease; Disorders of peroxisomal metabolism in adults; Hereditary disorders of oxalate metabolism the primary hyperoxalurias; Disturbances of acid base homeostasis; The acute phase response and C-reactive protein; Hereditary periodic fever syndrome; Amyloidosis; Alpha-1 antitrypsin deficiency and the serpinopathies; Section 13 - Endocrine disorders; Principles of hormone action; Disorders of the anterior pituitary gland; Disorders of the posterior pituitary gland; The thyroid gland and disorders of thyroid function; Thyroid cancer; Parathyroid disorders & diseases altering calcium metabolism; Disorders of the adrenal cortex; Congenital adrenal hyperplasia; Ovarian disorders; Disorders of male reproduction; Benign breast disease; Sexual dysfunction; Normal growth and its disorders; Normal puberty and its disorders; Normal and abnormal sexual differentiation; Pancreatic endocrine disorders & MEN; Diabetes mellitus; Hypoglycaemia; Hormonal manifestations of non-endocrine disorders; The pineal gland and melatonin; Section 14 - Medical disorders in pregnancy; Physiological changes of normal pregnancy; Nutrition in pregnancy; Medical management of normal pregnancy; Hypertension in pregnancy; Renal disease in pregnancy; Heart disease in pregnancy; Thrombosis in pregnancy; Chest disease in pregnancy; Liver and gastrointestinal disease during pregnancy; Diabetes in pregnancy; Endocrine disease in pregnancy; Neurological conditions in pregnancy; The skin in pregnancy; Autoimmune rheumatic disorders & vasculitis in pregnancy; Maternal infection in pregnancy; Fetal effects of maternal infection; Blood disorders in pregnancy; Malignant disease in pregnancy; Maternal critical care; Prescribing in pregnancy; Contraception for women with medical diseases; Section 15 - Gastroenterological disorders; Structure and function of the gastrointestinal tract; Symptoms of gastrointestinal disease; Colonoscopy and flexible sigmoidoscopy; Upper gastrointestinal endoscopy; Radiology of the gastrointestinal tract; Investigation of gastrointestinal function; The acute abdomen; Gastrointestinal Bleeding; Immune disorders of the gastrointestinal tract; The mouth and salivary glands; Diseases of the oesophagus; Peptic ulcer disease; Hormones and the gastrointestinal tract; Carcinoid syndrome; Differential diagnosis and investigation of malabsorption; Bacterial overgrowth of the small intestine; Coeliac disease; Gastrointestinal lymphomas; Disaccharidase Deficiency; Whipples Disease; Effects of massive bowel resection; Malabsorption syndromes in the Tropics; Crohns disease; Ulcerative colitis; Irritable bowel syndrome; Colonic diverticular disease; Congenital abnormalities of the gastrointestinal tract; Cancers of the gastrointestinal tract; Vascular disorders of the GI tract; Gastrointestinal infections; Miscellaneous disorders of the bowel; Structure and function of the liver, biliary tree and pancreas; Pathobiology of chronic liver disease; Investigation and management of jaundice; Cirrhosis and ascites; Portal hypertension and variceal bleeding; Hepatic encephalopathy; Liver failure; Liver transplantation; Hepatitis A to E; Autoimmune hepatitis; Primary biliary cholangitis; Primary sclerosing cholangitis; Alcoholic liver disease; Non-alcoholic fatty liver disease; Drug-induced liver disease; Vascular disorders of the liver; The liver in systemic disease; Primary and secondary liver tumours; Liver and biliary diseases in infancy and childhood; Diseases of the gallbladder and biliary tree; Acute pancreatitis; Chronic pancreatitis; Tumours of the pancreas; Section 16 - Cardiovascular disorders; Blood vessels and the endothelium; Cardiac physiology; Chest pain, breathlessness and fatigue; Syncope and palpitation; Electrocardiography; Echocardiography; Cardiac investigations:: nuclear, MRI and CT; Cardiac catheterisation and angiography; Cardiac arrhythmias; Epidemiology and general pathophysiological classification of heart failure; Acute heart failure:: definitions, investigation and management; Chronic heart failure:: definitions, investigation and management; Cardiorenal syndrome; Cardiac transplantation and mechanical circulatory support; Valvular heart disease; Myocarditis; The cardiomyopathies:: hypertrophic, dilated, restrictive and right ventricular; Speciac heart muscle disorders; Pericardial disease; Acute rheumatic fever; Endocarditis; Cardiac disease in HIV infection; Cardiovascular syphilis; Tumours of the heart; Cardiac involvement in genetic disease; Congenital heart disease in the adult; Biology & pathology of atherosclerosis; Coronary heart disease:: epidemiology and prevention; Management of stable angina; Management of acute coronary syndromes; Percutaneous interventional cardiac procedures; Coronary artery bypass and valve surgery; Acute aortic syndromes; Peripheral arterial disease; Cholesterol embolism; Structure and function of the pulmonary circulation; Pulmonary hypertension; Deep venous thrombosis and pulmonary embolism; Therapeutic anticoagulation; Essential hypertension:: definition, epidemiology and pathophysiology; Essential hypertension:: diagnosis, assessment and treatment; Secondary hypertension; Mendelian disorders causing hypertension; Hypertensive urgencies and emergencies; Chronic peripheral oedema and lymphoedema; Idiopathic oedema of women; Section 17 - Critical care; The clinical approach to the patient who is very ill; Cardiac arrest; Anaphylaxis; Preparing patients with medical conditions for major surgery; Acute respiratory failure; The circulation and circulatory support in the critically ill; Management of raised intracranial pressure; Sedation and analgesia in the ICU; Metabolic and endocrine changes in acute and chronic critical illness; Palliative and end of life care in the ICU; Neurological death and organ donation; Medical problems in ICU survivors; Section 18 - Respiratory disorders; The upper respiratory tract; Airways and alveoli; The clinical presentation of respiratory disease; Respiratory function tests; Thoracic imaging; Bronchoscopy, thoracoscopy and tissue biopsy; Upper respiratory tract infections; Pneumonia in the normal host; Nosocomial pneumonia; Mycobacteria; Pulmonary complications of HIV infection; Upper airway obstruction; Sleep-related breathing disorders; Allergic rhinitis; Asthma; Chronic obstructive pulmonary disease; Bronchiectasis; Cystic fibrosis; Diffuse parenchymal lung disease:: an introduction; Idiopathic pulmonary fibrosis; Bronchiolitis obliterans and cryptogenic organising pneumonia; The lung in autoimmune rheumatic disorders; The lung in vasculitis; Sarcoidosis; Pneumoconioses; Diffuse alveolar haemorrhage; Eosinophilic pneumonia; Lymphocytic infiltrations of the lung; Hypersensitivity pneumonitis; Pulmonary Langerhans cell histiocytosis; Lymphangioleiomyomatosis; Pulmonary alveolar proteinosis; Pulmonary amyloidosis; Lipoid (lipid) pneumonia; Pulmonary alveolar microlithiasis; Toxic gases and aerosols; Radiation pneumonitis; Drug-induced lung disease; Chronic Respiratory Failure; Lung transplantation; Pleural disease; Disorders of the thoracic cage and diaphragm; Lung cancer; Pulmonary metastases; Pleural tumours; Mediastinal tumours and cysts; Section 19 - Rheumatological disorders; Structure and function - Joints and connective tissue; Clinical presentation and diagnosis of rheumatological disorders; Clinical investigation; Back pain and regional disorders; Rheumatoid arthritis; Spondyloarthritis and related conditions; Infection and arthritis; Reactive arthritis; Osteoarthritis; Crystal-related arthropathies; Introduction; Systemic lupus erythematosus and related disorders; Systemic sclerosis; Sjogrens syndrome; Myositis; Large vessel vasculitis (Takayasu, GCA); ANCA associated vasculitis; Polyarteritis nodosa; Small vessel vasculitis; Behcets syndrome; Polymyalgia rheumatica; Kawasaki disease; Miscellaneous conditions presenting to the rheumatologist; Section 20 - Disorders of the skeleton; Skeletal disorders general approach and clinical conditions; Inherited defects of connective tissue:: Ehlers-Danlos syndrome, Marfans syndrome, and pseudoxanthoma elasticum; Osteomyelitis; Osteoporosis; Osteonecrosis, osteochondrosis, and osteochondritis dissecans; Bone cancer; Section 21 - Disorders of the kidney and urinary tract; Structure and function of the kidney; Disorders of water and sodium homeostasis; Disorders of potassium homeostasis; Clinical presentation of renal disease; Clinical investigation of renal disorders; Acute kidney injury; Chronic kidney disease; Haemodialysis; Peritoneal dialysis; Renal transplantation; Immunoglobulin A nephropathy and Henoch Schönlein purpura; Thin membrane nephropathy; Minimal change nephropathy and focal segmental glomerulosclerosis; Membranous nephropathy; Proliferative glomerulonephritis; Membranoproliferative glomerulonephritis; Anti-glomerular basement membrane disease; Acute tubulointerstitial nephritis; Chronic tubulointerstitial nephritis; Diabetes mellitus and the kidney; The kidney in systemic vasculitis; The kidney in rheumatological disorders; The kidney in sarcoidosis; Renal involvement in plasma cell dyscrasias, immunoglobulin-based amyloidoses, and fibrillary glomerulopathies, lymphomas, and leukaemias; Haemolytic uraemic syndrome; Sickle cell disease and the kidney; Infection-associated nephropathies; Malignancy-associated renal disease; Atherosclerotic renovascular disease; Renal disease in the tropics; Renal involvement in genetic disease; Urinary tract infection; Disorders of renal calcium handling, urinary stones, and nephrocalcinosis; The renal tubular acidoses; Disorders of tubular electrolyte handling; Urinary tract obstruction; Malignant disease of the urinary tract; Drugs and the kidney; Section 22 - Haematological disorders; Introduction to haematology; Cellular and molecular basis of haematopoiesis; Diagnostic techniques in the assessment of haematological malignancies; Granulocytes:: function and dysfunction; Myelodysplastic syndromes; Acute myeloid leukaemia; Chronic myeloid leukaemia; The polycythaemias; Thrombocytosis; Primary myelofibrosis; Eosinophilia; Histocytoses; Introduction to lymphopoiesis; Acute lymphoblastic leukaemia; Non-Hodgkin lymphoma; Hodgkin lymphoma; Chronic lymphocytic leukaemia; Plasma cell myeloma and related monoclonal gammopathies; Inherited bone marrow failure syndromes; Aplastic anaemia; Paroxysmal nocturnal haemoglobinuria; Introduction to erythropoiesis; Principles and classification of anaemia; Anaemia as a challenge to world health; Iron metabolism and its disorders; The anaemia of inflammation and chronic disease; Megaloblastic anaemia; Disorders of globin structure and function; Defective red cell maturation; Red cell membrane defects; Red cell enzyme defects; G6PD deficiency; Acquired haemolytic anaemias; Biology of haemostasis and thrombosis; Evaluation of the patient with a bleeding tendency; Thrombocytopenia and disorders of platelet function; Genetic disorders of coagulation; Acquired coagulation disorders; Blood transfusion; Transplantation; Section 23 - Disorders of the skin; Structure and function of the skin; Clinical approach to the diagnosis of skin disease; Inherited skin disease; Autoimmune bullous diseases; Papulosquamous disease; Dermatitis/eczema; Cutaneous vasculitis, connective tissue diseases, and urticaria; Disorders of pigmentation; Photosensitivity; Infections and the skin; Sebaceous and sweat gland disorders; Blood and lymphatic vessel disorders; Hair and nail disorders; Tumours of the skin; Skin and systemic disease; Cutaneous reactions to drugs; Management of skin disease; Section 24 - Neurological disorders; Introduction and approach to the patient with neurological disease; Mind and brain:: building bridges linking neurology, psychiatry, and psychology; Lumbar puncture; Electrophysiology of the central and peripheral nervous systems; Imaging in neurological diseases; Investigation of central motor pathways:: magnetic brain stimulation; Disturbances of higher cerebral function; Alzheimers disease and other dementias; Epilepsy in later childhood and adults; Narcolepsy; Sleep disorders; Syncope; The unconscious patient; Brain death and prolonged disorders of consciousness; Disorders of the visual pathways; Disorders of eye movements and balance; Disorders of auditory function; Subcortical structures:: the cerebellum, basal ganglia, and thalamus; Parkinsonism and other extrapyramidal diseases; Movement disorders other than Parkinson s disease; Ataxic disorders; Headache; Brainstem syndromes; Stroke:: cerebrovascular disease; Demyelinating disorders of the central nervous system; Traumatic brain injury; Intracranial tumours; Idiopathic intracranial hypertension; Bacterial infections; Viral infections; Intracranial abscess; Neurosyphilis and neuroAIDS; Human prion disease; Disorders of cranial nerves; Diseases of the spinal cord; Spinal cord injury and its management; Disorders of the autonomic nervous system; The motor neuron diseases; Diseases of the peripheral nerves; Inherited neurodegenerative diseases; Disorders of the neuromuscular junction; Structure and function of muscle; Muscular dystrophy; Myotonia; Metabolic and endocrine disorders; Mitochondrial disease; Developmental abnormalities of the central nervous system; Acquired metabolic disorders and the nervous system; Neurological complications of systemic disease; Paraneoplastic neurological syndromes; Autoimmune encephalitis and Morvan s syndrome; Section 25 - Disorders of the eye; The eye in general medicine; Section 26 - Psychiatric and drug-related disorders; General introduction; Psychiatric assessment of the medical patient; Confusion; Self-harm; Medically unexplained symptoms; Low mood; Psychopharmacology in medical practice; Psychological treatment in medical practice; Delirium; Dementia; Organic psychoses; Alcohol misuse; Substance misuse; Depression; Bipolar disorder; Anxiety disorders including OCD; Acute stress reactions, adjustment and PTSD; Eating disorders; Schizophrenia; Somatic symptom disorders and CFS; Personality disorder; Brief interventions for excessive alcohol consumption; Obesity and weight management; Smoking cessation; Liaison psychiatry; Section 27 - Forensic medicine; Forensic and legal medicine; Section 28 - Sports and exercise medicine; Sports and exercise medicine; Section 29 - Biochemistry in medicine; The use of biochemical analysis for diagnosis and management; Section 30 - Acute Medicine; Acute medical presentations; Practical Procedures;