In this issue of Thoracic Surgery Clinics, guest editor Dr. Alessandro Wasum Mariani brings his considerable expertise to the topic of Surgical Management of Pleuropulmonary Infectious Diseases. The surgical management of pleuropulmonary infectious diseases requires a nuanced understanding of various surgical techniques and the ability to adapt to the evolving landscape of infectious pathogens. In this issue, top experts cover key topics that lead to improved patient care and a better understanding of the ongoing challenges posed by these serious infections.